Results 151 to 160 of about 219,811 (315)

Nodule-in-Nodule Hepatocellular Carcinoma

Radiology: Imaging Cancer
Zakaryae Essouni, Amine Naggar, Kaoutar Imrani, Nabil Moatassim Billah, Ittimade Nassar   +4 more
openaire   +2 more sources

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

Advanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun, Ruiqi Wu, Qingshuang Tang, Yunli Xu, Wanrui Shi, Mengxin Wang, Haonan Wang, Yan Luo, Cheng Ma, Xiaolong Liang   +9 more
wiley   +1 more source

RBM25 Drives Hepatocellular Carcinoma Progression by Stabilizing YAP Through Regulating Oncogenic Splicing‐switch of MYPT1

Advanced Science, EarlyView.
This study establishes that the RBM25‐PRPF40A interaction modulates MYPT1 splicing, promoting the production of the oncogenic long isoform. This isoform stabilizes YAP by suppressing its phosphorylation and subsequent proteasomal degradation, ultimately accelerating tumor growth.
Wenjing Zhang, Lili Zhi, Tian Huang, Lingya Feng, Chaoqun Chen, Huanhuan Wei, Xiaolong Liu, Lei Chen, Jinrui Zhang, Ge Zhang, Baofeng Zhao, Rong Liu, Dan Chen, Yangfan Qi, Yang Wang   +14 more
wiley   +1 more source

Pulmonary Nodules [PDF]

JAMA, 2021
openaire   +2 more sources

Hierarchical Nanoplatform Integrating Oxidative–Acidic Microenvironment Remodeling and Bone Homeostasis Modulation for Diabetic Bone Defect Therapy

Advanced Science, EarlyView.
A hierarchical CM/LDH nanoplatform integrates ROS‐scavenging Ce‐MOF nanozymes with acid‐neutralizing CaAl‐LDH and is delivered within GelMA hydrogel to diabetic bone defects. By remodeling the oxidative‐acidic microenvironment, preserving mitochondrial homeostasis, and suppressing mtDNA–cGAS–STING inflammatory signaling, CM/LDH reduces proinflammatory ...
Xu Chen, Xingyu Zhu, Zhixin Qiu, Yijia Zhu, Xinhui Zheng, Dongqi Fan, Jinglei Zhan, Congxiu Mao, Ping Ji, Tao Chen, Qingqing He   +10 more
wiley   +1 more source

Tumor growth rate as a new imaging biomarker in early detection of lung cancer. [PDF]

Cancer Imaging
Oudkerk M.
europepmc   +1 more source

Physiological Studies on Nodule Formation: II. The Influence of Delayed Inoculation on the Rate of Nodulation in Red clover

, 1949
IN of the the introductory rates of nodule paper and of lateral this series root (Nutman, formation 1948) on plants a study of red was clover made of the rates of nodule and lateral root formation on plants of red clover which had been selected for low ...
Nutman, P. S.
core  

Puerarin‑Loaded pH‑Responsive ZIF‑90 Nanoparticles Ameliorate Osteoporosis via Enhancing H3K18 Lactylation and Suppressing Aberrant Osteoclast Activation

Advanced Science, EarlyView.
Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu, Yue Xi, Sheng Wang, Ye Chen, Jiajie Yang, Xiaojian Shi   +5 more
wiley   +1 more source

High-Throughput Peptide Array Clinical Validation for Lung Adenocarcinoma Detection

ACS Omega
Shengli Yang, Peixian Li, Xiaowen Zhang, Zhipeng Liu, Dan Zhou, Yihao Chen, Zhuxing Chen, Yaming Xiong   +7 more
doaj   +1 more source

Ruptured benign thyroid nodule post-radiofrequency ablation. [PDF]

JCEM Case Rep
Dang C, Andrade AA.
europepmc   +1 more source