Results 111 to 120 of about 106,365 (264)

Trametinib, a MEK1/2 Inhibitor, Protects Mice from Cisplatin- and Noise-Induced Hearing Loss

Pharmaceuticals
Hearing loss is one of the most common types of disability; however, there is only one FDA-approved drug to prevent any type of hearing loss. Treatment with the highly effective chemotherapy agent, cisplatin, and exposure to high-decibel noises are two ...
Richard D. Lutze, Matthew A. Ingersoll, Regina G. Kelmann, Tal Teitz   +3 more
doaj   +1 more source

Efficacy of a combined drug therapy for ameliorating noise-induced hearing loss [PDF]

, 2011
Experiments investigated the median effective dose of antiepileptic drugs and synthetic glucocorticoids for the prevention and treatment of noise-induced hearing loss for C57BL/6J mice.
Luxmore, Randi Lynn
core   +1 more source

Severe Hearing Loss in the World's First Successfully Captive‐Born Yangtze Finless Porpoise: Impact of High Underwater Sound Exposure and Congenital Hearing Disorders

Integrative Zoology, EarlyView.
The audiogram of the world's first successfully captive‐born Yangtze finless porpoise was on average 40 dB higher than conspecifics. Congenital hearing disorders and noise exposure may be the primary cause of porpoise's hearing loss. ABSTRACT Aquariums globally have seen significant growth in recent decades.
Zhitao Wang, Tomonari Akamatsu, Kexiong Wang, Ding Wang   +3 more
wiley   +1 more source

Decoding Dual Regulatory Layers: Integrating Differential Expression and Alternative Splicing Dynamics in the Evolution of Laryngeal Echolocation Across Chiropteran Lineages

Integrative Zoology, EarlyView.
We integrated short‐read and long‐read RNA‐seq data from cochlear tissues of echolocating and non‐echolocating bats to disentangle transcriptional and post‐transcriptional regulation. Echolocating bats showed neural‐function enrichment among differentially expressed genes, while alternatively spliced genes were linked to epigenetic regulation. Overlaps
Jianyu Wu, Daoyuan Hu, Min Chen, Xiuguang Mao   +3 more
wiley   +1 more source

Developing a Questionnaire to Assess Noise Exposure in Children and Teens [PDF]

, 2007
Until recently, children and teenagers were not thought to be an at-risk population for noise induced hearing loss (NIHL). As MP3 players have grown in popularity, there has been an increased awareness of possible noise exposure and hearing loss in ...
Penafiel, Emie
core   +1 more source

Iron Ore Pricing in China: Financialization Through a Marxist Lens

Abacus, EarlyView.
We offer a Marxist interpretation of financialization as we examine the Chinese market for iron ore and the shift in the pricing mechanism from an annual fixed price to an indexed price from 2010. Drawing upon Marx's theory of the circuit of capital, we illustrate an empirical case of financialization that results from the conflict between social ...
Xun Gong, Eagle Zhang, Corinne Cortese
wiley   +1 more source

Field Validation of a Standard Hearing Loss Prediction Model in an Iranian Textile Industry

International Journal of Occupational Hygiene, 2017
Noise is the most frequent physical agent in workplace that effects on hearing loss. This study aimed to investigate the value of noise exposure in different jobs along with noise induced permanent threshold shift of workers, prediction of hearing ...
REZA JAFARI NODOUSHAN, MOHAMMAD REZA MONAZZAM ESMAIELPOUR, MOHAMMAD REZA GHOTBI RAVANDI, AMIR HOUSHANG MEHRPARVAR, REZA GHOLAMEZADEH   +4 more
doaj  

Attitude of university students towards the leisure noise induced tinnitus and hearing loss

Journal Riphah College of Rehabilitation Sciences, 2021
Background Structures that process sound and empower the brain to understand are called ears. This is the procedure in which analysis of sound signal is done through intensity and frequency.
Shumaila Malik, Sumera Nawaz Malik, Fazaila Ehsan, Waqas Azeem   +3 more
doaj  

Long-Term Effects of the Synergistic Interaction of Cisplatin and Noise [PDF]

, 2015
As cancer treatments advance, more patients survive each year. Of these survivors, many have experienced treatment with chemotherapeutic drugs like cisplatin that have aided in and enabled their recovery. Cisplatin, a chemotherapeutic drug used to combat
DeBacker, J. Riley
core  

The policy adjacent: How affordable housing generates policy feedback among neighboring residents

American Journal of Political Science, EarlyView.
Abstract While scholars have documented feedback effects among a policy's direct winners and losers, less is known about whether such effects can occur among the indirectly affected—“the policy adjacent.” Using 458 geocoded housing developments built between two nearly identical statewide ballot propositions funding affordable housing in California, we
Michael Hankinson, Asya Magazinnik, Melissa Sands   +2 more
wiley   +1 more source