Results 31 to 40 of about 7,906 (299)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Noise landing charges and passengers' choice of airport. [PDF]

open access: yes, 1995
This study demonstrates how aircraft noise can be translated into a form of landing charge. The objectives of the thesis were to develop noise landi'ng charges for six of the major airports in England and to determine what the implication it has on ...
Yeahiya, Mohammed
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Certification Testing [PDF]

open access: yes, 1996
Wind turbine certification is becoming increasingly important for companies competing in the international marketplace. In support of the U.S. wind energy industry, the National Renewable Energy Laboratory (NREL) now offers testing services at the ...

core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Noise measurement of a quadrotor drone in an anechoic chamber

open access: yes, 2023
Operation of drones near densely populated urban areas can cause significant noise pollution issues. Drone noise measurements in controllable environments are essential for noise certification.
Liu, Guangsheng   +5 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

GNSS constellation simulator and digital signal generator for receiver test, qualification and certification

open access: yes, 2022
7 S.This paper presents the overall concept and architectural design of a deterministic GNSS Constellation Simulator and Digital Signal Generator.
Wasle, E.   +5 more
core  

Comparison of predicted engine core noise with proposd FAA helicopter noise certification requirements [PDF]

open access: yesThe Journal of the Acoustical Society of America, 1981
Calculated engine core noise levels, based on NASA-Lewis prediction procedures, for five representative helicopter engines are compared with measured total helicopter noise levels and proposed FAA helicopter noise certification requirements. Comparisons are made for approach, level flyover, and takeoff procedures.
U. von Glahn, D. Groesbeck
openaire   +1 more source

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