Results 31 to 40 of about 9,216,494 (260)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Mokslas: Lietuvos Ateitis, 2013 Along with an increase in the aircraft engine power and growth in air traffic, noise level at airports and their surrounding environs significantly increases. Aircraft noise is high level noise spreading within large radius and intensively irritating the
Monika Bartkevičiūtė +1 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A novel noise assessment method based on human core competency
Xibei Gongye Daxue Xuebao, 2023 The tough noise environment in helicopter cockpit can passively influence pilots in mental and physical way, weaken their core competency, and as a result, maybe causing pilot error and even accidents.
ZHANG Xiaoyan, CHENG Jiaao, XUE Hongjun
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Vehicle Impact on Tire Road Noise and Validation of an Algorithm to Virtually Change Tires
Applied Sciences, 2022 Especially for electric vehicles, the tire impact on car noise is becoming more and more important. The requirement of meeting certification criteria makes estimating the sound pressure level essential for vehicle manufacturers.
Michael Leupolz, Frank Gauterin
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
AIRPORT NOISE CHARGES AND LOCAL COMMUNITIES: APPLICATION TO REGIONAL AIRPORTS [PDF]
Journal of Engineering Science and Technology, 2016 There have always been conflicts among airports and local communities due to the aeronautical noise generated by airport operations. In fact, this is a factor that - if not properly managed - could severely cut down the growth of air traffic in an ...
LUCA MANTECCHINI
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source