Results 61 to 70 of about 203,102 (303)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

SEISMONOISY: A Quasi-Real-Time Seismic Noise Network Monitoring System

Sensors
This paper introduces SEISMONOISY, an application designed for monitoring the spatiotemporal characteristic and variability of the seismic noise of an entire seismic network with a quasi-real-time monitoring approach.
Giuseppe Ruzza, Rocco Cogliano, Ciriaco D’Ambrosio, Luigi Falco, Vincenzo Cardinale, Felice Minichiello, Antonino Memmolo, Angelo Castagnozzi, Giovanni De Luca, Annamaria Vicari   +9 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

An Automatic Denoising Method with Estimation of Noise Level and Detection of Noise Variability in Continuous Glucose Monitoring

IFAC-PapersOnLine, 2016
Abstract Although continuous glucose monitoring (CGM) devices have been the crucial part of the artificial pancreas, their success has been discounted by random measurement noise. The difficulty of denoising methods for CGM is that the filter parameters are hard to be determined to well reflect the real noise level.
Hong Zhao, Chunhui Zhao
openaire   +1 more source

A case study on sound level monitoring and management at large-scale music festivals [PDF]

, 2019
Sound level management at live events has been made immeasurably easier over the past decade or so through use of commercially-available sound level monitoring software.
Mulder, Johannes, Mulder, J., Burton, J., Kok, Marcel, Berrios, Anthony, Hill, A.J., Kok, M., Hill, Adam J., Kociper, Alex, Berrios, A., Kociper, A.   +10 more
core  

Clustering analyses to assess HVAC noise in real-world conditions

, 2022
The assessment of systems' noise during measurements is usually carried out in an empty state of the spaces under study. Long-term monitoring in real-world conditions can provide insights into the performance of systems during the day.
Garai M., De Salvio D., D'Orazio D.
core  

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Noise pollution mitigation and control in urban areas near international borders through 2D noise mapping

Scientific Reports
Noise pollution is defined as any disturbing or unwanted sound that disrupts or harms human health or wildlife. Noise pollution can have profound effects on both human health and the environment.
Pervez Alam, Tarique Ahmad, Lubna Maqbool, Raisul Islam, Shadab Ahmad, Mufeed Sharholy   +5 more
doaj   +1 more source