Results 31 to 40 of about 1,624,283 (243)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Static characteristics of CMOS digital circuit based on transition metal dichalcogenide transistors

AIP Advances, 2019
Static characteristics of digital combinational logic circuits and Schmitt triggers based on two-dimensional (2D) transition metal dichalcogenides (TMDs) have been systematically explored.
F. F. Mao, Z. Jin, L. Y. Shang, Z. G. Hu, J. H. Chu   +4 more
doaj   +1 more source

Stability Enhancement and Noise Reduction of an Axial Compressor with Foam Metal Casing Treatment

Aerospace, 2022
Foam metal is a foam-like substance with a high porosity; it has been used in flow control, vibration abatement, and acoustic absorption, mainly based on its physical properties.
Jia Li, Xu Dong, Dakun Sun, Yuqing Wang, Chunwang Geng, Xiaofeng Sun   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Increasing the noise margin in organic circuits using dual gate field-effect transistors [PDF]

, 2008
Complex digital circuits reliably work when the noise margin of the logic gates is sufficiently high. For p-type only inverters, the noise margin is typically about 1 V.
Blom, P. W. M., Smits, E.C.P., Saint Come, Y. Bon, Spijkman, M., de Leeuw, D. M., D. M. de Leeuw, Cantatore, E., Bon Saint Côme, Y., M. Spijkman, P. W. M. Blom, Blom, P.W.M., Leeuw, de, D.M., Y. Bon Saint Côme, E. C. P. Smits, Smits, E. C. P., Setayesh, S., S. Setayesh, E. Cantatore   +17 more
core   +1 more source

Effects of graded noise levels on behavior, physiology and production performance of intensively managed lambs

Italian Journal of Animal Science, 2010
The aim of the experiment was to assess the effects of graded noise levels on behavioral, immune and cortisol respons-  es, and on production performance of forty precocious Merino lambs. The experiment lasted 42 days and was preceded  by a two-
Donato Casamassima, Gina Evelina Colella, Angelo Nardomarino, Agostino Sevi, Angelo Quaranta   +4 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Ultra-Low Power, Process-Tolerant 10T (PT10T) SRAM with Improved Read/Write Ability for Internet of Things (IoT) Applications

Journal of Low Power Electronics and Applications, 2017
In this paper, an ultra-low power (ULP) 10T static random access memory (SRAM) is presented for Internet of Things (IoT) applications, which operates at sub-threshold voltage. The proposed SRAM has the tendency to operate at low supply voltages with high
Pooran Singh, Santosh Kumar Vishvakarma
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source