Results 61 to 70 of about 192,763 (285)

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Using Downstream DPSK and Upstream Wavelength-Shifted ASK for Rayleigh Backscattering Mitigation in TDM-PON to WDM-PON Migration Scheme

IEEE Photonics Journal, 2013
A migration scheme from time-division-multiplex passive optical network (TDM-PON) to wavelength-division-multiplex PON (WDM-PON) using differential phase-shift keying (DPSK) for the downstream signal and wavelength-shifted amplitude-shift keying (WS-ASK)
C. W. Chow, C. H. Yeh
doaj   +1 more source

A Result of Accidental Noise Pollution: Acoustic Flowmeters Emit 28 kHz Pulses That May Affect Harbor Porpoise Hearing

Frontiers in Marine Science, 2022
Large rivers like the Elbe or the Weser are periodically entered by harbor porpoises of the North Sea. They may even move 97 km upstream to the port of Hamburg, where their presence is highest in spring.
Tobias Schaffeld, Joseph G. Schnitzler, Andreas Ruser, Johannes Baltzer, Max Schuster, Ursula Siebert   +5 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Noise-agnostic quantum error mitigation with data augmented neural models

npj Quantum Information
Quantum error mitigation, a data processing technique for recovering the statistics of target processes from their noisy version, is a crucial task for near-term quantum technologies.
Manwen Liao, Yan Zhu, Giulio Chiribella, Yuxiang Yang   +3 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Phase-Noise Mitigation in OFDM by Best Match Trajectories

, 2015
This paper proposes a novel approach to phase-noise compensation. The basic idea is to approximate the phase-noise statistics by a finite number of realizations, i.e., a phase-noise codebook.
Händel, Peter, Negusse, Senay, Zetterberg, Per   +2 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Control of Large Wind Energy Converters for Aeroacoustic Noise Mitigation with Minimal Power Reduction

Energies
The population is often opposed to wind turbines being erected near their homes, mainly because the machines are noisy, especially at night. In an effort to establish a compromise between the needs of the people and the fulfilment of energy demands, wind
Andrea Rivarola, Adrian Gambier
doaj   +1 more source