Results 71 to 80 of about 3,612,179 (299)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Machine Learning-Enhanced 3D GIS Urban Noise Mapping with Multi-Modal Factors

open access: yesISPRS International Journal of Geo-Information
Geographic Information System (GIS)-based noise management is crucial in urban environments as it provides precise spatial analysis, helping to identify noise hotspots and optimize noise control measures.
Jianping Pan   +6 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

RTS noise impact in CMOS image sensors readout circuit [PDF]

open access: yes, 2009
CMOS image sensors are nowadays widely used in imaging applications even for high end applications. This is really possible thanks to a reduction of noise obtained, among others, by Correlated Double Sampling (CDS) readout.
P. Magnan   +3 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Investigation of a smart noise barrier for dual active and passive control of construction noise

open access: yes, 2023
49th International Congress and Exposition on Noise Control Engineering (INTERNOISE 2020): Advances in Noise and Vibration Control Technology: Seoul, Korea, 23-26 August 2020202312 bcchVersion of RecordOthersEnvironment and Conservation Fund of the Hong ...
Wang, J   +4 more
core  

From models to reality: how CNOSSOS-EU and ISO 9613-2 perform against measured road traffic noise

open access: yesNoise Mapping
Road traffic noise is a significant environmental risk factor to the human health, resulting in the necessity for accurate noise prediction models with less uncertainty. Several standards and methods are available in commercial noise modeling software to
Odeh Omar, Kocsis Dénes
doaj   +1 more source

On noise modeling in a nerve fibre

open access: yesApplied Mathematics Letters, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
A. Samoletov, Bakhtier Vasiev
openaire   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Home - About - Disclaimer - Privacy