Results 41 to 50 of about 3,712,884 (293)

Assessing Traffic Noise and Its Impact on High-Rise Apartment Buildings Adjacent to an Urban Expressway: A Case Study in Chengdu, China

Buildings
With rapid urbanization, traffic growth has accelerated in some cities in China. Due to strict urban construction land utilization policies, many high-rise apartment buildings have been constructed adjacent to expressways. To better understand the impact
Heng Yu, Ailing Li
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Smart Solutions for Recreational Noise Pollution in Turkey

Noise Mapping, 2018
Environmental noise has become an important issue in urban life quality. Policy makers, local authorities and researchers have been trying to solve this issue in a smart way.
Çoban Nilgün Akbulut, Dalkılıç Cengiz, Kaya Sezer, Türkmenoğlu Mevlüt, Çoban Mustafa   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Noise assesment and mitigation schemes for Estonian airports

Aviation, 2009
In recent years, concern over airport noise and its impact on surrounding communities has been spurred by the continual growth in air traffic together with urban development in close proximity to many airports around the world.
Signe Vanker, Mart Enneveer, Imre Rammul
doaj   +1 more source

Citizen noise pollution monitoring

, 2009
Peer ...
Maisonneuve, Nicolas, Stevens, Matthias, Niessen, Maria E., Hanappe, Peter, Steels, Luc   +4 more
openaire   +5 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The Study and Development of BPM Noise Monitoring at the Siam Photon Source

Particles
This study presents the development of a noise-monitoring system for the storage ring at the Siam Photon Source, designed to detect and classify noise patterns in real time using beam position monitor (BPM) data. Noise patterns were categorized into four
Wanisa Promdee, Sukho Kongtawong, Surakawin Suebka, Thapakron Pulampong, Natthawut Suradet, Roengrut Rujanakraikarn, Puttimate Hirunuran, Siriwan Jummunt   +7 more
doaj   +1 more source