Results 111 to 120 of about 608,210 (316)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Modeling the Measurements of Cochlear Microcirculation and Hearing Function after Loud Noise [PDF]

, 2011
Objective: Recent findings support the crucial role of microcirculatory disturbance and ischemia for hearing impairment especially after noise-induced hearing loss (NIHL).
Canis, Martin, Arpornchayanon, Warangkana, Strieth, Sebastian, Markus Suckfuell, Sebastian Strieth, Bernhard Olzowy, Olzowy, Bernhard, Suckfuell, Markus, Ihler, Fritz, Martin Canis, Warangkana Arpornchayanon, Fritz Ihler   +11 more
core   +1 more source

Structural Parameters of Star Clusters: Signal to Noise Effects

Open Astronomy, 2015
We study the impact of photometric signal to noise on the accuracy of derived structural parameters of unresolved star clusters using MCMC model fitting techniques.
Narbutis D., Bridžius A., Semionov D.
doaj   +1 more source

Effect of the environmental parameters on the noise diffusion

, 2006
An experimental work was carried out in an open field having 10000 m2 area purified from any noise on 121 survey stations using the central frequencies of 7 different octave bands with a single and double sources of noise. Meteorological parameters such as temperature, humidity, atmospheric pressure, velocity and direction of wind were also taken into ...
Şensöğüt, Cem, Çınar, İbrahim
openaire   +2 more sources

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Use of fan rig data for the understanding and prediction of fan broadband noise and noise changes due to a variable area nozzle

, 2009
This thesis presents the results of the research component of this EngD, entitledUse of fan rig data for the understanding and prediction of fan broadband noise and noisechanges due to a variable area nozzleAs suggested by the title, fan rig noise ...
Deane, Eugene Pio
core  

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

White Noises on Different Stokes Components of Six Millisecond Pulsars

The Astrophysical Journal
We presented measurements of jitter noise and radiometer noise for the Stokes parameters I , L , and V in six millisecond pulsars from the International Pulsar Timing Array sample, based on FAST observations.
S. N. Sun, N. Wang, W. M. Yan
doaj   +1 more source

Discordance Between Systemic Lupus Erythematosus Disease Activity Index Domain Weights and Their Association With Organ Damage Accrual

Arthritis Care &Research, EarlyView.
Objective Studies of damage accrual in patients with systemic lupus erythematosus (SLE) show associations with disease activity measured by the SLE Disease Activity Index 2000 (SLEDAI‐2K), but these associations are imperfect. SLEDAI scores are powerfully influenced by weightings (1–8) assigned to each domain.
Kevin Zhang, Eric F. Morand, Sarah E. Boyd, François Petitjean, Alberta Hoi, Rachel Koelmeyer, Iolanda Miceli, Julie A. Monk, Hieu T. Nim   +8 more
wiley   +1 more source

The Effect of Noise Reduction Measures on the Perception of Railway Noise

, 2015
The A-weighted sound pressure level is a commonly used quantity to assess the effect of noise reduction measures. However, psychoacoustic variables, in particular loudness, are assumed to better explain perceived annoyance.
Kaseß, Christian, Maly, Thomas, Majdak, Piotr, Waubke, Holger   +3 more
core