This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian +5 more
wiley +1 more source
Measurement noise attenuation in modified Smith predictor and automatic offset controllers for integrator plus dead-time system. [PDF]
Huba M, Bistak P, Vrancic D.
europepmc +1 more source
This study introduces a novel chloro boron subphthalocyanine/polymer blend OFET sensor achieving 0.005 ppb limit of detection for ammonia at room temperature and high selectivity against similar amines. An original theoretical framework is proposed to describe the sensing mechanism, relating analyte molecular volume and Lewis basicity to sensor ...
Kavinraaj Ella Elangovan +6 more
wiley +1 more source
Advanced image reconstruction algorithms for high-resolution digital time-of-flight PET/CT enhance visualization of sub-clinical internal mammary lymph node metastases in breast cancer: a phantom and a clinical, retrospective cohort study. [PDF]
Satoh Y +11 more
europepmc +1 more source
Reducing power consumption in spintronic memory remains a major challenge due to the need for high current densities. A bilayer of gadolinium and holmium iron garnets enables purely temperature‐induced, nonvolatile magnetic switching with bistable states within a ±25 K range. This approach achieves up to 66‐fold lower energy use than current spin–orbit
Junseok Kim +3 more
wiley +1 more source
Enhanced muscle MRI using deep learning: shorter acquisition time with improved image quality. [PDF]
Fan P +10 more
europepmc +1 more source
Gourd‐Inspired Design of Unit Cell with Multiple Gradients for Physiological‐Range Pressure Sensing
Gourd‐shaped micro‐dome arrays with coordinated modulus, conductivity, and geometric gradients co‐optimize sensitivity and linearity in piezoresistive tactile sensors. Under pressure, a solid upper dome embeds into a porous lower dome, triggering rapid contact‐area growth and series‐to‐parallel conduction, enabling unsaturated, intensity‐resolved ...
Jiayi Xu +6 more
wiley +1 more source
Vibration Signal Denoising Method Based on ICFO-SVMD and Improved Wavelet Thresholding. [PDF]
Cui Y, He X, Wu Z, Zhang Q, Cao Y.
europepmc +1 more source
Sustainable Catalyst‐Free PLG Networks: Recyclability, Biodegradability, and Functional Performance
A catalyst‐additive free covalent adaptable network is developed from star‐shaped poly(lactide‐co‐glycolide) cross‐linked with pyromellitic dianhydride, enabling internal carboxylic acid‐driven transesterification. The resulting biodegradable network exhibits mechanical robustness (Young's modulus ≈1.6 GPa), complete recyclability, rapid biodegradation
Lars Schwarzer +2 more
wiley +1 more source

