Results 41 to 50 of about 9,252 (214)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Design of Offset–Free Predictive Control with State–Space Models: Equivalences and New Results

International Journal of Applied Mathematics and Computer Science
Design of offset-free model predictive control (MPC) with a linear state-space process model is discussed in the paper, for deterministic constant or asymptotically constant external and internal (modeling errors) disturbances.
Tatjewski Piotr
doaj   +1 more source

Improving Error Estimates for Evaluating Satellite-Based Atmospheric CO₂ Measurement Concepts through Numerical Simulations

Remote Sensing
To assess the accuracy of satellite monitoring of anthropogenic CO2 emissions, inversions of satellite data in SWIR are usually combined with the assimilation of the total CO2 column into a Kalman filter that reconstructs the sources and sinks of ...
Bruna Barbosa Silveira, Vincent Cassé, Olivier Chomette, Cyril Crevoisier   +3 more
doaj   +1 more source

Experimental Study on the Effect of Urban Road Traffic Noise on Heart Rate Variability of Noise-Sensitive People

Frontiers in Psychology, 2022
Epidemiological studies have confirmed that long-term exposure to road traffic noise can cause cardiovascular diseases (CDs), and when noise exposure reaches a certain level, the risk of related CDs significantly increases.
Chao Cai, Yanan Xu, Yan Wang, Qikun Wang, Lu Liu   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Psychometric Properties of the Bangla Version of Weinstein Noise Sensitivity Scale Short Form (NSS‐SF‐BV) Among Bangladeshi Individuals: A Cross‐Sectional Study

Health Science Reports
Background and Aims The Weinstein Noise Sensitivity Scale (NSS) was developed to measure the noise sensitivity of the students. However, until now, NSS tools have not been adapted or assessed for psychometric properties in Bangla.
Pramath Chandra Sarker, Md. Nur‐E‐Alam Siddique, Sabina Sultana   +2 more
doaj   +1 more source

Psychoacoustic Evaluation of Shared-Bike Electronic Alert Sounds: Effects of Brand, Sound Pressure Level, and Occurrence Frequency on Annoyance

Applied Sciences
This paper examines the subjective annoyance associated with shared-bike electronic alert sounds (SBeASs), an emerging urban noise source. A study was conducted by employing extensive questionnaire surveys and psychoacoustic experiments.
Kaishi Meng, Linda Liang, Yang Song
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A revised model of noise sensitivity

Environmental Research: Health
Earlier definitions of noise sensitivity implicitly presupposed that some sounds can objectively be defined as noise and that some people are intrinsically more sensitive to it.
Jiana Wu, Kim N Dirks, Daniel Shepherd, David Welch   +3 more
doaj   +1 more source