Results 71 to 80 of about 3,343,706 (271)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Patterns of physiological and affective responses to vehicle pass-by noises

Noise and Health, 2013
Traffic noise is considered causing annoyance and severe health effects like cardiovascular disease (CVD). The present laboratory study examines the importance of individual factors, namely age, gender and personality traits on short term physiological ...
Gert Notbohm, Renate Schmook, Sieglinde Schwarze, Peter Angerer   +3 more
doaj   +1 more source

Linear amplifiers with phase-sensitive noise [PDF]

Physical Review A, 1987
We present a model for a linear amplifier which adds phase-dependent noise to the input signal. This is achieved by preparing the internal modes of the amplifier in a squeezed vacuum. Such a scheme could be used to amplify a squeezed-signal quadrature with reduced added noise compared with conventional schemes.
Milburn, G. J., Steyn-Ross, M. L., Walls, D. F.   +2 more
openaire   +4 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Noise Sensitivities in Dogs: An Exploration of Signs in Dogs with and without Musculoskeletal Pain Using Qualitative Content Analysis

Frontiers in Veterinary Science, 2018
Noise sensitivity is a common behaviour problem in dogs. In humans, there is a well-established relationship between painful conditions and the development of fear-related avoidance responses.
Ana Luisa Lopes Fagundes, Lynn Hewison, Kevin J. McPeake, Helen Zulch, Daniel Simon Mills   +4 more
doaj   +1 more source

On the Noise Sensitivity of the Randomized SVD

IEEE Transactions on Information Theory
The randomized singular value decomposition (R-SVD) is a popular sketching-based algorithm for efficiently computing the partial SVD of a large matrix. When the matrix is low-rank, the R-SVD produces its partial SVD exactly; but when the rank is large, it only yields an approximation.
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Statistical analysis based on a two-staged SEM-SVM approach for environmental noise annoyance prediction and identification of influencing factors [PDF]

International Journal of Human Capital in Urban Management
BACKGROUND AND OBJECTIVES: Noise pollution is an environmental stressor that is mainly caused due to heavy transportation in urban scenarios. Traffic noise is a growing concern in urban environments, impacting public health and well-being.
M. Rehman, M. Kamal, S. Tiwari
doaj   +1 more source

Noise maps for acoustically sensitive navigation [PDF]

SPIE Proceedings, 2004
More and more robotic applications are equipping robots with microphones to improve the sensory information available to them. However, in most applications the auditory task is very low-level, only processing data and providing auditory event information to higher-level navigation routines.
Martinson, Eric, Arkin, Ronald C.
openaire   +1 more source