Results 71 to 80 of about 1,238,186 (282)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Sensitivity Studies for Third-Generation Gravitational Wave Observatories [PDF]

, 2010
Advanced gravitational wave detectors, currently under construction, are expected to directly observe gravitational wave signals of astrophysical origin.
Abernathy, M., Acernese, F., Amaro-Seoane, P., Andersson, N., Arun, K., Barone, F., Barr, B., Barsuglia, M., Beker, M., Beveridge, N., Birindelli, S., Bose, S., Bosi, L., Braccini, S., Bradaschia, C., Brand, J. van den, Broeck, C. van den, Bulik, T., Calloni, E., Cella, G., Chelkowski, S., Chincarini, A., Clark, J., Coccia, E., Colacino, C., Colas, J., Cumming, A., Cunningham, L., Cuoco, E., Danilishin, S., Danzmann, K., De Rosa, R., De Salvo, R., Dent, T., Di Fiore, L., Di Virgilio, A., Doets, M., Fafone, V., Falferi, P., Flaminio, R., Franc, J., Frasconi, F., Freise, A., Friedrich, D., Fulda, P., Gair, J., Gemme, G., Genin, E., Gennai, A., Giazotto, A., Glampedakis, K., Granata, M., Grote, H., Gräf, C., Guidi, G., Gurkovsky, A., Hammond, G., Hannam, M., Harms, J., Heinert, D., Hendry, M., Heng, I., Hennes, E., Hild, S., Hough, J., Husa, S., Huttner, S., Jones, G., Khalili, F., Kokeyama, K., Kokkotas, K., Krishnan, B., Li, T. G. F., Lorenzini, M., Lück, H., Majorana, E., Mandel, I., Mandic, V., Mantovani, M., Martin, I., Michel, C., Minenkov, Y., Morgado, N., Mosca, S., Mottin, E. Chassande, Mours, B, Murray, P., Müller-Ebhardt, H., Nawrodt, R., Nelson, J., Oshaughnessy, R., Ott, C. D., Palomba, C., Paoli, A., Parguez, G., Pasqualetti, A., Passaquieti, R., Passuello, D., Pinard, L., Plastino, W., Poggiani1, R., Popolizio, P., Prato, M., Punturo, M., Puppo, P., Rabeling, D., Rapagnani, P., Read, J., Regimbau, T., Rehbein, H., Reid, S., Ricci, F., Richard, F., Rocchi, A., Rowan, S., Rüdiger, A., Santamaría, L., Sassolas, B., Sathyaprakash, B., Schnabel, R., Schwarz, C., Seidel, P., Sintes, A., Somiya, K., Speirits, F., Strain, K., Strigin, S, Sutton, P., Tarabrin, S., Thüring, A., van Veggel, M., Vecchio, A., Veitch, J., Vetrano, F., Vicere, A., Vyatchanin, S., Willke, B., Woan, G., Yamamoto, K.   +138 more
core   +3 more sources

Contrast sensitivity, healthy aging and noise

Vision Research, 2013
At least three studies have used external noise paradigms to investigate the cause of contrast sensitivity losses due to healthy aging. These studies have used noise that was spatiotemporally localized on the target. Yet, Allard and Cavanagh (2011) have recently shown that the processing strategy can change with localized noise thereby violating the ...
Allard, Rémy, Renaud, Judith, Molinatti, Sandra, Faubert, Jocelyn   +3 more
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A revised model of noise sensitivity

Environmental Research: Health
Earlier definitions of noise sensitivity implicitly presupposed that some sounds can objectively be defined as noise and that some people are intrinsically more sensitive to it.
Jiana Wu, Kim N Dirks, Daniel Shepherd, David Welch   +3 more
doaj   +1 more source

Quantum limits in interferometric measurements

, 2001
Quantum noise limits the sensitivity of interferometric measurements. It is generally admitted that it leads to an ultimate sensitivity, the ``standard quantum limit''.
, , Braginski V B, Brillet A, Brillet A, Gea-Banacloche J, Gea-Banacloche J, Kimble H J, Loudon R, M. T Jaekel, Meystre P, Reynaud S, Reynaud S, S Reynaud, Tombesi P   +14 more
core   +1 more source

Geometric Influences II: Correlation Inequalities and Noise Sensitivity [PDF]

, 2012
In a recent paper, we presented a new definition of influences in product spaces of continuous distributions, and showed that analogues of the most fundamental results on discrete influences, such as the KKL theorem, hold for the new definition in ...
Keller, Nathan, Mossel, Elchanan, Sen, Arnab   +2 more
core   +4 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The associations between noise sensitivity, reported physical and mental health, perceived environmental quality, and noise annoyance

Noise and Health, 2010
One hundred and ninety residents around Frankfurt Airport (46% female; 17-80 years) were interviewed concerning noise annoyance due to transportation noise (aircraft, road traffic), perceived mental and physical health, perceived environmental quality ...
Dirk Schreckenberg, Barbara Griefahn, Markus Meis   +2 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source