Early Synovial Regulatory T Cell Engagement in Posttraumatic Osteoarthritis
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early postinjury biologic processes within the synovium shape disease trajectories. We investigated whether synovial Treg cells are engaged during the early phase following joint injury and whether experimental enrichment of this ...
Xueyou Zhang +5 more
wiley +1 more source
Teacher-delivered transdiagnostic child mental healthcare in rural Indian primary schools (Tealeaf): study protocol for a batched stepped-wedge cluster randomized controlled trial with a hybrid effectiveness-implementation-context design. [PDF]
Matergia M +9 more
europepmc +1 more source
Objective A new algorithm enables the identification of patients with polymyalgia rheumatica (PMR) across health care sectors in Denmark. We estimated annual incidence rates from 2003 to 2024 and described the disease course, including the occurrence of late‐onset giant cell arteritis (GCA) and prednisolone or prednisone (PDN) treatment.
Agnete Overgaard Donskov +4 more
wiley +1 more source
When healthy classrooms hurt: how reduced bullying isolates victimized youth through altered friendship and status dynamics. [PDF]
Hoffmann T, Basa B, Kollár KN.
europepmc +1 more source
Body donor programs in Australia and New Zealand: Current status and future opportunities
Abstract Body donation is critical to anatomy study in Australia and New Zealand. Annually, more than 10,000 students, anatomists, researchers, and clinicians access tissue donated by local consented donors through university‐based body donation programs. However, little research has been published about their operations.
Rebekah A. Jenkin, Kevin A. Keay
wiley +1 more source
Tumor regression grades in locally advanced gastroesophageal adenocarcinoma: associations with survival, pathological risk factors, and molecular biomarkers in a 19-year real-world cohort. [PDF]
Puhr HC +14 more
europepmc +1 more source
AS Executive Committee Nominees (Bios and Vision Statements) 4-19-2018
AS Executive Committee Nominees (Bios and Vision Statements) 4-19 ...
Nominations Committee +1 more
core
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola +5 more
wiley +1 more source
An exploratory study to investigate the effects of motor performance and maturation on talent selection in handball. [PDF]
Brüning L +3 more
europepmc +1 more source
Aim The shortage of trained clinical assessors in African National Regulatory Authorities (NRAs) poses a challenge to effective regulatory decision‐making. Developed in line with the World Health Organization's (WHO) Global Competency Framework (WHO‐GCF), a university‐certified short course, Dossier assessment for clinical assessors in Africa, was ...
Stephanie Leigh +19 more
wiley +1 more source

