Results 221 to 230 of about 16,499,389 (322)

Assessing Capability Complexity Using Enterprise Architecture Framework

open access: yesSystems Engineering, EarlyView.
ABSTRACT This study proposes a structured and quantitative methodology to evaluate the holistic complexity of system‐of‐systems (SoSs), employing the Zachman Architecture Framework (ZAF) as its foundational analytical tool. A five‐phase analytical procedure is developed and empirically validated, encompassing: (1) refinement of complexity measures, (2)
Javad Bakhshi, Mahmoud Efatmaneshnik
wiley   +1 more source

A Proposal to Center Relevance in Applied Linguistics Research: The Relevance‐to‐Practice (RTP) Framework

open access: yesTESOL Quarterly, EarlyView.
Abstract Considering applied linguistics as a problem‐centered discipline, we address an enduring challenge in the field: the need to ensure that research provides findings that can contribute to solving everyday challenges faced by language practitioners.
Hyun‐Bin Hwang, Matthew D. Coss
wiley   +1 more source

Integrative Bioinformatics, Experimental Validation, and Interpretable Machine Learning Reveal Oxyresveratrol‐Mediated Protection Against Cadmium‐Induced Lung Adenocarcinoma‐Related Transcriptional Dysregulation

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a toxic heavy metal strongly implicated in lung adenocarcinoma (LUAD) through mechanisms involving oxidative stress, epigenetic dysregulation, and chronic inflammation. This study aimed to identify Cd‐responsive genes associated with LUAD and to evaluate the protective effects of oxyresveratrol (O‐RES) against Cd‐induced ...
Murat Isıyel, Hamid Ceylan, Yeliz Demir
wiley   +1 more source

Occurrence of <i>Trichinella</i> spp. infestations in black bears in Quebec, Canada. [PDF]

open access: yesJ Vet Diagn Invest
Krückemeier S   +2 more
europepmc   +1 more source

“For three of my four miscarriages I was at work…” Experiences of miscarriage, infertility and assisted fertility in veterinary workplaces

open access: yesVeterinary Record, EarlyView.
Abstract Background Miscarriage, infertility and assisted fertility (MIAF) can profoundly impact physical and mental health. The aims of this study were to investigate how veterinary professionals’ work environments and employers impacted their experiences of MIAF and to identify how workplace experiences of MIAF could be improved.
Jenny Stavisky   +3 more
wiley   +1 more source

Descriptive Epidemiology of the 2022-2023 Cholera Outbreak in Lebanon and Lessons Learned in the Context of a Humanitarian Emergency Situation. [PDF]

open access: yesOpen Forum Infect Dis
Abiad F   +11 more
europepmc   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

open access: yesVIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy