Results 201 to 210 of about 165,366 (392)

Deciphering the Immunomodulatory Function of GSN+ Inflammatory Cancer‐Associated Fibroblasts in Renal Cell Carcinoma Immunotherapy: Insights From Pan‐Cancer Single‐Cell Landscape and Spatial Transcriptomics Analysis

open access: yesCell Proliferation, EarlyView.
Pan‐cancer scRNA‐seq and ST‐seq analyses identify GSN+ inflammatory cancer‐associated fibroblasts (CAFs) and their spatial distribution in immune checkpoint inhibitor (ICI) therapy. The Caf.Sig model accurately predicts ICI response across cancers using CAF gene signatures and machine learning.
Shan Li   +18 more
wiley   +1 more source

Endocrine Resistance Score Based on Three Key Genes Predicts Prognosis and Reveals Potential Therapeutic Targets for ER+HER2− Breast Cancer

open access: yesCell Proliferation, EarlyView.
We generated endocrine‐resistant BC cell lines and identified CLEC3A, PCDH10, and ST3GAL1 as key endocrine‐resistant genes. More importantly, we validated their role in mediating resistance through PI3K‐AKT signalling and developed a predictive ERS with strong clinical relevance.
Liqin Ping   +7 more
wiley   +1 more source

Evaluation of Multiple Tissue Levels Frequently Upstages Patients With Clinically Localized Thin Primary Cutaneous Melanoma

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Breslow thickness (BT), ulceration, and microsatellitosis are critical prognostic parameters for cutaneous melanoma staging. These parameters can vary depending on the number of tissue levels examined from individual paraffin blocks.
Louise A. Jackett   +2 more
wiley   +1 more source

Pharmacokinetics of Cefaclor and Cephalexin: Dosage Nomograms for Impaired Renal Function [PDF]

open access: green, 1978
Daniel A. Spyker   +3 more
openalex   +1 more source

Anomia prehabilitation in temporal lobe epilepsy surgery: A pilot study

open access: yesEpilepsia, EarlyView.
Abstract Objective An emerging approach in surgery is to propose prehabilitation programs to strengthen the patient's functional abilities before surgical interventions, thus helping them cope better with its consequences. In drug‐resistant language‐dominant temporal lobe epilepsy (LdTLE), surgical treatment carries a risk of increasing cognitive ...
Véronique Sabadell   +12 more
wiley   +1 more source

Аналіз впливу маси пасажира на модель ідентифікації злітної ваги та центрівки літака

open access: yes, 2014
This article provides a new model of the take-off weight and balance of the aircraft determining process, as well as the weight distribution of passengers’ law.
Miroshnitchenko, Mariy   +5 more
core  

Application of a nomogram to gradient elution chromatography

open access: hybrid, 1960
Huber R. Warner, William E.M. Lands
openalex   +1 more source

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