Results 201 to 210 of about 106,048 (268)

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, Volume 13, Issue 10, Page 2088-2101, October 2026.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

Advanced Science, Volume 13, Issue 56, 9 October 2026.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang, Hongjie Gao, Bifei Zhang, Xuetian Li, Ding Li, Aihua Cao, Fengyin Sun   +6 more
wiley   +1 more source

Hypomethylation of GNA15 Promotes Pancreatic Ductal Adenocarcinoma Progression and Macrophage M2 Polarization via STAT3‐CXCL8 Axis

Advanced Science, Volume 13, Issue 59, 23 October 2026.
A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo, Zhenyuan Qian, Lei Wang, Weilang Xu, Yuxin Weng, Kai Jiang, Zaiyuan Ye, Ji Xu, Guangyuan Song   +8 more
wiley   +1 more source

Predicting acute kidney injury in type B aortic dissection: development and validation of a clinical nomogram. [PDF]

Clinics (Sao Paulo)
Chen W, Li Z, Shu X.
europepmc   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, Volume 101, Issue 10, Page 2632-2651, October 2026.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Development and internal validation of a nomogram-based screening tool for concurrent autoimmune hepatitis in children with intestinal diseases: a retrospective cohort study. [PDF]

Front Med (Lausanne)
Hou Y.
europepmc   +1 more source

An Analysis of Factors Influencing Comorbid Anxiety and Depression Among Adults in China: A Large‐Scale Cross‐Sectional Study

Brain and Behavior, Volume 16, Issue 10, October 2026.
In 51,774 Chinese adults, insomnia, irregular diet, prolonged device use, and physical chronic disease were associated with higher odds of comorbid anxiety and depression, whereas older age, marriage, and moderate daily steps were protective. Screening for insomnia and modifiable lifestyle factors may help identify those at risk.
Zhuoqun Chen, Jiaying Huang, Yuying Wang, Jingxian Chen, Ke Zhu, Tongjie Chen, Xin‐lin Chen, Wenyan Tan   +7 more
wiley   +1 more source