Results 31 to 40 of about 72,806 (269)

A nomogram incorporating linezolid and metabolite concentrations for predicting linezolid induced thrombocytopenia in patients with renal impairment

Scientific Reports
A nomogram to estimate the risk of linezolid-induced thrombocytopenia in patients with renal impairment is not available. The aim of the study is to develop a nomogram for predicting linezolid-induced thrombocytopenia in patients with renal impairment ...
Hanzhen Zhao, Lian Tang, Zhiwei Zhuang, Ying Zhang, Jingjing Li, Lufen Duan, Lu Shi, Chenqi Zhu, Jian Lu, Yunlong Yuan, Qian Zhang, Yanxia Yu, Jinhui Xu   +12 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A novel risk-predicted nomogram for sepsis associated-acute kidney injury among critically ill patients

BMC Nephrology, 2021
Background Acute kidney injury (AKI) is a prevalent and severe complication of sepsis contributing to high morbidity and mortality among critically ill patients. In this retrospective study, we develop a novel risk-predicted nomogram of sepsis associated-
Shanglin Yang, Tingting Su, Lina Huang, Lu-Huai Feng, Tianbao Liao   +4 more
doaj   +1 more source

A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention

Frontiers in Cardiovascular Medicine, 2022
Background and aimsEarly detection of mortality after percutaneous coronary intervention (PCI) is crucial, whereas most risk prediction models are based on outdated cohorts before the year 2000.
Jingjing Song, Yupeng Liu, Yupeng Liu, Wenyao Wang, Wenyao Wang, Jing Chen, Jie Yang, Jun Wen, Jun Gao, Jun Gao, Chunli Shao, Chunli Shao, Yi-Da Tang, Yi-Da Tang   +13 more
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Construction of a preoperative nomogram model for predicting perineural invasion in advanced gastric cancer

Frontiers in Medicine
ObjectiveThis study aimed to develop and validate a clinical and imaging-based nomogram for preoperatively predicting perineural invasion (PNI) in advanced gastric cancer.MethodsA retrospective cohort of 351 patients with advanced gastric cancer who ...
Ruochen Cong, Ruonan Xu, Jialei Ming, Zhengqi Zhu   +3 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Nomogram to Predict Internal Mammary Lymph Nodes Metastasis in Patients With Breast Cancer

Frontiers in Oncology, 2019
Background: Numerous studies have showed that internal mammary lymph node (IMLN) metastasis is an important adverse prognostic factor in patients with breast cancer (BC), however, there are no available prediction model for the preoperative diagnosis of ...
Xinhua Xie, Zhenchong Xiong, Xing Li, Xiaojia Huang, Feng Ye, Hailin Tang, Xiaoming Xie   +6 more
doaj   +1 more source

Prognostic nomogram for cancer-specific survival in patients with intrahepatic cholangiocarcinoma after hepatectomy: A population study of 919 patients

Frontiers in Surgery, 2023
Background and AimsIntrahepatic cholangiocarcinoma has an increasing global incidence and mortality rate. Hepatectomy is still the most effective curative treatment for patients with ICC, but the prognosis of patients with ICC is still poor even after ...
Gaobo Huang, Gaobo Huang, Weilun Song, Weilun Song, Yanchao Zhang, Yanchao Zhang, Bingyi Ren, Bingyi Ren, Yi Lv, Yi Lv, Kang Liu, Kang Liu   +11 more
doaj   +1 more source