Results 231 to 240 of about 33,934 (312)

From Molecules to Machines: An Integrative Framework Linking Molecular Pathogenesis, Multi‐Factorial Risk, Risk Stratification, Clinical Management, and Artificial Intelligence in QT Prolongation and Sudden Cardiac Death

open access: yesClinical Cardiology, Volume 49, Issue 6, June 2026.
An integrative conceptual framework linking the five principal domains addressed in this review. Beginning at the molecular level, loss‐of‐function mutations in KCNQ1 and KCNH2 reduce outward repolarizing currents (IKs and IKr), while gain‐of‐function SCN5A mutations augment late inward sodium current (INa), establishing the genetic substrate for ...
Mojtaba Farjam   +2 more
wiley   +1 more source

Clinical and Pathological Characteristics and Prognosis of Breast Cancer During Pregnancy and Postpartum: A Multicenter Retrospective Study

open access: yesCancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Purpose The prognostic impact of the interval between the most recent childbirth and breast cancer diagnosis remains insufficiently defined, particularly when breast cancer diagnosed during pregnancy (PrBC) is distinguished from postpartum breast cancer (PPBC).
Liying Wang   +5 more
wiley   +1 more source

Assessment of Multiple Prognostic Scores in Patients With Metastatic Renal Cell Carcinoma Receiving First‐Line, Immune‐Based Combinations

open access: yesCancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Combination immunotherapy is widely used as first‐line treatment for metastatic renal cell carcinoma (mRCC), but pretreatment prognostic stratification remains insufficiently established. Aims To evaluate the performance of various prognostic scores in the first‐line treatment of metastatic renal cell carcinoma (mRCC) with ...
Hiromichi Sakurai   +16 more
wiley   +1 more source

Venous thromboembolism and bleeding in cancer patients: role of inflammatory and cardiac biomarkers. [PDF]

open access: yesEur Heart J
Roy DC   +6 more
europepmc   +1 more source

Decoding Choroid Plexus Pathology in Alzheimer's Disease: A Longitudinal Radiomics Approach for Prodromal Identification and Risk Stratification

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
A machine learning model utilizing choroid plexus (CP) radiomics effectively distinguishes Alzheimer's disease (AD) from mild cognitive impairment (MCI) and predicts MCI‐to‐AD progression risk. After integration with clinical features, the model exhibits strong predictive performance. The CP radiomics features correlate significantly with cognitive and
Feiyue Yin   +13 more
wiley   +1 more source

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