Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Synergistic Tribofilm Growth in Ethylene Glycol: A Dual-Additive Approach for Superior Lubrication. [PDF]
Wen X +5 more
europepmc +1 more source
Cash non-additive risk measures: horizon risk and generalized entropy [PDF]
Giulia Di Nunno, Emanuela Rosazza Gianin
openalex +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Enhancing clinical insights in glioma grading using Bayesian Optimization and Explainable AI. [PDF]
Elsayad AM, Elsayad OA.
europepmc +1 more source
Comonotonically additive functional and regular non-additive measure
identifier:oai:t2r2.star.titech.ac.jp ...
openaire
A Quantiled Study of Dynamic Generalized Non-Additive Entropy Measure for Record Value
Susela Devi, Vinod Bhatia
openalex +2 more sources
On additive and non-additive measures of directed divergence [PDF]
M. Behara, Prem Nath
openalex
MEASURING THE EFFECTS OF POLLINATORS AND HERBIVORES: EVIDENCE FOR NON-ADDITIVITY IN A PERENNIAL HERB
Carlos M. Herrera
openalex +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source

