FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Genomic dissection of hoof and leg conformation in Swiss dairy cattle populations reveals polygenic architecture and a recessive HYAL1 nonsense variant affecting longevity in Holstein cattle. [PDF]
Genet Sel EvolVasiljevic S +10 more
europepmc +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
A Representation of Preferences by the Choquet Integral with Respect to a 2-Additive Capacity [PDF]
In the context of Multiple criteria decision analysis, we present the necessary and sufficient conditions allowing to represent an ordinal preferential information provided by the decision maker by a Choquet integral w.r.t a 2-additive capacity.
Michel Grabisch +2 more
core
Machine learning models of depressive symptoms in middle-aged and elderly patients with chronic kidney disease: A cross-sectional study based on CHARLS. [PDF]
Medicine (Baltimore)Wang J, Wang J, Meng M, Jin J.
europepmc +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
An Algorithm for Clustered Data Generalized Additive Modelling with S-PLUS [PDF]
We present a set of functions in S-PLUS to implement the clustered data generalized additive marginal modelling (CDGAM) strategy proposed by Berhane and Tibshirani (1998).
Vincent Carey, Lin Yee Hin
core
Outlier detection in state-space models using mean-shift penalisation. [PDF]
Stat ComputShankar R +3 more
europepmc +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
A characterization of the 2-additive Choquet integral through cardinal information [PDF]
In the context of multiple criteria decision analysis, we present the necessary and sufficient conditions to represent a cardinal preferential information by the Choquet integral w.r.t. a 2-additive capacity.
Michel Grabisch +2 more
core