Results 221 to 230 of about 765,619 (251)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Machine Learning-Assisted Optimisation of the Laser Beam Powder Bed Fusion (PBF-LB) Process Parameters of H13 Tool Steel Fabricated on a Preheated to 350 ^∘C Building Platform. [PDF]

Materials (Basel)
Kosarava K, Widomski P, Ziętala M, Dobras D, Muzyk M, Wysocki BA.   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The impact of high temperature, noise, benzene compounds, and shift work on renal function abnormalities in oil workers: a cohort study in China. [PDF]

J Health Popul Nutr
Li Z, Si Z, Zhang S, Wang N, Zhang H, Li X, Xue L, Wu J.   +7 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Exploring the association between dexmedetomidine and all-cause mortality in mechanically ventilated patients with sepsis through propensity score matching analysis and machine learning algorithms: a MIMIC-IV retrospective study. [PDF]

Front Cell Infect Microbiol
Wei Y, Li M, Wang P, Zhou J, Lu K, Huang H, Huang Y, Lin F.   +7 more
europepmc   +1 more source

Benchmarking non-additive genetic effects on polygenic prediction and machine learning-based approaches

Bell NY, Wightman DP, de Leeuw C, Posthuma D.   +3 more
europepmc   +1 more source

Clinical implications of rare and common variation in preimplantation genetic testing for breast cancer. [PDF]

NPJ Genom Med
Lencz T, Bhattacharyya U, Klausner L, John J, Carmi S.   +4 more
europepmc   +1 more source

Artificial Intelligence Informed Hydrogel Biomaterials in Additive Manufacturing. [PDF]

Gels
Zhang Z, Tao ZZ, Du R, Huo R, Zheng X.
europepmc   +1 more source

Interactions with polygenic background impact quantitative traits in the UK Biobank

Ferreira LAF, Hu S, Davies RW, Myers SR.
europepmc   +1 more source