Results 121 to 130 of about 16,858,371 (288)

Dominance of capacities by k-additive belief functions

, 2006
International audienceIn this paper we deal with the set of $k$-additive belieffunctions dominating a given capacity. We follow the lineintroduced by Chateauneuf and Jaffray for dominating probabilities and continued by Grabisch for general $k$-additive ...
Grabisch, Michel, Gil Álvarez, Pedro, Miranda Menéndez, Pedro, Gil, Pedro, Miranda, Pedro   +4 more
core   +1 more source

Experimental Study of the Kinematics of a Double-Row Planetary Mechanism Using Two Elliptical External Gears

Advanced Engineering Research
Introduction. Mechanisms with non-circular gears are of wide interest to researchers and inventors due to their compactness and the implementation of a wide range of transfer functions.
A. A. Prikhodko, N. N. Belina, A. V. Novitskiy, M. M. Shchetinin   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Cdkn2a/p16Ink4a loss impairs Spatial memory independently of Alzheimer’s-associated genetic pathways in young adult mice

Cellular and Molecular Life Sciences
Background The cyclin-dependent kinase inhibitor CDKN2A/p16INK4A (p16INK4A) is a central regulator of cellular senescence, widely studied in ageing and cancer.
Pauline Stephan, Damien Plassard, William M. Keyes, Yann Hérault   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The uniform distributions puzzle. [PDF]

This note deepens a problem proposed and discussed by Kadane and O'Hagan (JASA, 1995). Kadane and O'Hagan discuss the existence of a uniform probability on the set of natural numbers (they provide a su_cient and necessary condition for the existence of ...
Lauwers, Luc
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Nonparametric estimation of an additive quantile regression model [PDF]

This paper is concerned with estimating the additive components of a nonparametric additive quantile regression model. We develop an estimator that is asymptotically normally distributed with a rate of convergence in probability of n-r/(2r+1) when the ...
Sokbae 'Simon' Lee, Joel Horowitz
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Physics-constrained deep clustering for integrated reservoir classification and differential fracturing design in shale formations

International Journal of Coal Science & Technology
Shale reservoirs exhibit complex geological characteristics including ultra-low permeability, nanoscale pores, and significant heterogeneity, making them challenging yet essential unconventional energy resources.
Yuxuan Deng, Wendong Wang, Yuliang Su, Xinyu Zhuang, Mingwei Jia, Feng Jia   +5 more
doaj   +1 more source