Results 31 to 40 of about 634,856 (265)

Feminism and Pornography: From Mainstream Pornography (Hetero-Patriarchal) to Post-Porn (Non Binary)

open access: yesAge of Human Rights Journal, 2022
Along with prostitution, and more recently surrogate motherhood, pornography has been a contentious issue within the feminist movement ever since the 1970s.
Ana Valero Heredia
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Breaking the Binary: How Clinicians Can Ensure Everyone Receives High Quality Reproductive Health Services

open access: yesOpen Access Journal of Contraception, 2023
Christina Jung,1 Adam Hunter,1 Mona Saleh,2 Gwendolyn P Quinn,1 Siripanth Nippita1 1Department of Obstetrics and Gynecology, New York University Grossman School of Medicine, New York, NY, USA; 2Division of Gynecologic Oncology, Department of Obstetrics &
Jung C   +4 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Non-Binary and Intersex Visibility and Erasure in Roman Archaeology

open access: yesTheoretical Roman Archaeology Journal, 2020
An issue being tackled in modern, particularly western, archaeology is the assumption that something intrinsic to a scholar’s own culture is an etic in space and time.
Miller Joseph Power
doaj   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

‘Are We Gonna Have to Pretend to Be a Straight Couple?’: Examining the Specific Detriment that Cisgenderism Places on Non-Binary Adoption and Fostering Applicants in the United Kingdom

open access: yesBehavioral Sciences
This exploratory qualitative study aimed to find out more about how the children’s social work system interacts with non-binary parents. It highlights the specific detriment that can be faced by non-binary people hoping to adopt or foster in the United ...
Claire Brown
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Associations Among Religiosity, Religious Rejection, Mental Health, and Suicidal Ideation in Transgender and Gender Nonconforming Adults

open access: yesBehavioral Sciences
Objectives: Religiosity has generally been shown to be a protective factor against adverse mental health in the general population. Transgender and gender non-conforming (TGNC) individuals, however, may not experience the same protective effects, as many
Steph L. Cull   +2 more
doaj   +1 more source

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