Results 231 to 240 of about 344,689 (283)

Language-Specific Differences in Large Language Model Diagnostic Reasoning: A Translation-Controlled Clinical Vignette Study. [PDF]

J Clin Med
Ibrahim-El-Nur JM, Kaczmarek W, Winiarska W, Kuś A, Łoś M.   +4 more
europepmc   +1 more source

Harnessing Large Language Models to Advance Microbiome Research: From Sequence Analysis to Clinical Applications

Advanced Intelligent Discovery, EarlyView.
Large language models are transforming microbiome research by enabling advanced sequence profiling, functional prediction, and association mining across complex datasets. They automate microbial classification and disease‐state recognition, improving cross‐study integration and clinical diagnostics.
Jieqi Xing, He Wang, Yangyang Sun, Xiaoquan Su, Shunyao Wu   +4 more
wiley   +1 more source

Development and validation of search hedges for Transgender and Gender Diverse (TGD) populations in Ovid MEDLINE and Ovid APA PsycInfo. [PDF]

PLoS One
Gagen R, Marsalis S, Dinh C, Applejohn M, Shah R, Tong OX, Marshall Z, Everhart A.   +7 more
europepmc   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

Moderate-severe traumatic brain injury disrupts core mechanisms of online language processing and use. [PDF]

Cortex
Lord KM, Kekes-Szabo S, Sherlock P, Duff MC, Brown-Schmidt S.   +4 more
europepmc   +1 more source

Advanced Experiment Design Strategies for Drug Development

Advanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang, Anthony Harker, Mohan Edirisinghe, Maryam Parhizkar   +3 more
wiley   +1 more source

The relationship between cognitive complaints and burden of non-cognitive symptoms in multiple sclerosis. [PDF]

BJPsych Open
Roberts S, Kuznetsova V, D'Aprano F, Zheng CJ, Kalincik T, Malpas CB.   +5 more
europepmc   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Is one run enough? Reproducibility of flagship large language models across temperature and reasoning settings in biomedical text processing. [PDF]

J Am Med Inform Assoc
Windisch P, Koechli C, Dennstädt F, Aebersold DM, Zwahlen DR, Förster R, Schröder C.   +6 more
europepmc   +1 more source

Data‐Guided Photocatalysis: Supervised Machine Learning in Water Splitting and CO2 Conversion

Advanced Intelligent Discovery, EarlyView.
This review highlights recent advances in supervised machine learning (ML) for photocatalysis, emphasizing methods to optimize photocatalyst properties and design materials for solar‐driven water splitting and CO2 reduction. Key applications, challenges, and future directions are discussed, offering a practical framework for integrating ML into the ...
Paul Rossener Regonia, Christian Mark Pelicano   +1 more
wiley   +1 more source