Results 241 to 250 of about 1,710,776 (381)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Non-communicable disease burden in China, 1990-2023: Evidence from the Global Burden of Disease Study 2023. [PDF]

Chin Med J (Engl)
Zhang T, Jiang H, Xu X, Zhao Z, Zhou M.
europepmc   +1 more source

Non-Communicable Diseases and Oral Health

Indian Journal of Dental Research, 2022
openaire   +3 more sources

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Pathway to developing paediatric non-communicable disease guidelines in Malawi: a scoping review. [PDF]

BMC Health Serv Res
Moyo D, Nagase M, Msekandiana A, Phoya F, Chimowa T, Molyneux EM, Weigel R, Mbale E, Banda JC, Krüger C, Chimalizeni Y.   +10 more
europepmc   +1 more source

Non-Communicable Diseases: A Major Problem Worldwide

, 2016
Quek Kia Fatt
openalex   +1 more source

DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption

Advanced Functional Materials, EarlyView.
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim, Dai‐Hwan Kim, Priyannth R. Sundharbaabu, Chae Yeon Lee, Jina Bae, Jiyu Hyun, Young‐Ju Jang, Haeni Kim, Min‐Ho Hong, Juewen Liu, Tobias Fey, Suk Ho Bhang, Jun Hyuk Heo, Jung Heon Lee   +13 more
wiley   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

How happy is healthy enough? Uncovering the happiness threshold for global non-communicable disease prevention. [PDF]

Front Med (Lausanne)
Iuga IC, Jafri SR, Iuga H.
europepmc   +1 more source

Non-communicable diseases and risk factors profiling among geriatric population residing in Hyderabad city, India

Karthikeyan Ramanujam, Joyeeta Thakur, Rajitha Triveni Koralla, JJ Babu Geddam, Samarasimha Reddy N   +4 more
openalex   +1 more source