Results 71 to 80 of about 152,213 (313)

Prevalence, awareness, treatment, control, and treatment-control rates of hypertension among adults in Hubei province: a cross-sectional survey

open access: yesZhongguo gonggong weisheng
ObjectiveTo investigate the prevalence, awareness, treatment, control, and treatment-control rates of hypertension among adults in Hubei province, and to provide a reference for the prevention and control of hypertension in this region.
Tianjing HE   +7 more
doaj   +1 more source

Can China achieve a one-third reduction in premature mortality from non-communicable diseases by 2030?

open access: yesBMC Medicine, 2017
Background The United Nation’s Sustainable Development Goals for 2030 include reducing premature mortality from non-communicable diseases (NCDs) by one third.
Yichong Li   +14 more
doaj   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

open access: yesFEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo   +4 more
wiley   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

open access: yesFEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu   +9 more
wiley   +1 more source

Knowledge, attitudes, and beliefs regarding acute coronary syndrome in patients with type 2 diabetes: a cross-sectional study

open access: yesDiscover Public Health
Introduction Cardiovascular diseases are one of the leading causes of mortality and disability among individuals with diabetes. Cardiac mortality in these patients is often associated with the prevalence of silent ischemia.
Mohammad Amerzadeh   +4 more
doaj   +1 more source

Impact of Lung Cancer Deaths on Life Expectancy and Years of Potential Life Lost from 1981 to 2015 in Kunshan, Jiangsu Province, China

open access: yesChinese Journal of Lung Cancer, 2017
Background and objective Previous reports have shown that lung cancer incidence and mortality were increasing both in male and female; however, the temporal trends in lung cancer eliminated life expectancy and potential years of life lost (PYLL) are very
Wenbin HU   +9 more
doaj   +1 more source

Enhanced analysis of gating latency in 0.35T MR‐linac through innovative time synchronization of a motion phantom and plastic scintillation detector

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to evaluate how different gantry angles, breathing rates (BPM), cine image speeds, and tracking algorithms affect beam on/off latency and the subsequent impact on target dose for a 0.35T MR‐Linac with a 6 MV FFF beam.
Mateb Al Khalifa   +4 more
wiley   +1 more source

Evaluation of a community-based hypertension improvement program (ComHIP) in Ghana: data from a baseline survey

open access: yesBMC Public Health, 2017
Background Ghana faces an increasing burden of non-communicable disease with rates of hypertension estimated as high as 36% in adults. Despite these high rates, hypertension control remains very poor in Ghana (4%).
Peter Lamptey   +8 more
doaj   +1 more source

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