Results 81 to 90 of about 1,519,430 (297)

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Joint Effect of Central Obesity and Family History on Hypertension in Type 2 Diabetes: A Cross-Sectional Study in China

open access: yesDiabetes, Metabolic Syndrome and Obesity
Xiangyu Chen, Lijin Chen, Ruying Hu, Weiyuan Yao, Zhimin Ma, Jieming Zhong Department of Non-Communicable Disease Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, 310051, People’s Republic of ...
Chen X   +5 more
doaj  

Projections of esophageal cancer incidence trend in Jiangsu Province, China: a Bayesian modeling study

open access: yesJournal of the National Cancer Center
Objective: Esophageal cancer has made a great contribution to the cancer burden in Jiangsu Province, East China. This study was aimed at reporting esophageal cancer incidence trend in 2009–2019 and its prediction to 2030.
Weigang Miao   +6 more
doaj   +1 more source

Pattern, correlates and implications of non-communicable disease multimorbidity among older adults in selected Indian states: a cross-sectional study

open access: yesBMJ Open, 2017
Objectives The objective of the present study was to estimate the proportion of older adults with non-communicable disease (NCD) multimorbidity, its correlates and implications in selected Indian states. Methods The study used data of 9852 older adults (≥
G. K. Mini, K. Thankappan
semanticscholar   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Adequate iodine nutrition and higher salt intake in Chinese adults aged 18–59 years recommended by international organizations

open access: yesScientific Reports
Iodine deficiency and excessive salt intake have adverse health effects. This study evaluated the iodine level and salt intake in Chinese adults aged 18–59 years after implementing the salt reduction program and compared with both the World Health ...
Diqun Chen   +6 more
doaj   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

Tuberculosis non-communicable disease comorbidity and multimorbidity in public primary care patients in South Africa

open access: yesAfrican Journal of Primary Health Care & Family Medicine, 2018
Background Little is known about the prevalence of non-communicable disease (NCD) multimorbidity among tuberculosis (TB) patients in Africa. Aim and setting The aim of this study was to assess the prevalence of NCD multimorbidity, its pattern and impact ...
K. Peltzer
semanticscholar   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

Effect of TyG combined with obesity indicators on prevalence of hypertension and hyperuricemia comorbidity among residents aged 35 years and older in Hebei province: a surveillance data analysis

open access: yesZhongguo gonggong weisheng
ObjectiveTo investigate the effect of the triglyceride-glucose index (TyG) combined with various obesity indicators on the prevalence of comorbid hypertension and hyperuricemia among residents aged 35 years and older in Hebei province, and to provide a ...
Lijuan TANG   +7 more
doaj   +1 more source

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