Results 61 to 70 of about 1,896,004 (266)

Air-Coupled Lamb Wave Testing of Buried Air-Voids in Foam-Filled Sandwich Panels

IEEE Open Journal of Ultrasonics, Ferroelectrics, and Frequency Control
Sandwich panels, composed of two steel faces and a rigid foam core, are an inexpensive and lightweight option for construction industry. However, voids can form in the foam core during the manufacturing process.
Christoph Haugwitz, Andre Reinartz, Jan-Helge Dorsam, Sonja Wismath, Gianni Allevato, Jan Hinrichs, Paulina Gorol, Annalena Kuhn, Thomas Hahn-Jose, Jorg Lange, Mario Kupnik   +10 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A Review of Visual Estimation Research on Live Pig Weight

Sensors
The weight of live pigs is directly related to their health, nutrition management, disease prevention and control, and the overall economic benefits to livestock enterprises.
Zhaoyang Wang, Qifeng Li, Qinyang Yu, Wentai Qian, Ronghua Gao, Rong Wang, Tonghui Wu, Xuwen Li   +7 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Dynamic test methods for natural frequency of footbridge

Journal of Measurement Science and Instrumentation, 2013
Using environmental random vibration as the excitation,traditional accelerometer method,non-contact video method and non-contact laser method were employed to determine the natural frequency of Kunyu River footbridge.All the results of these three ...
WANG Cai-feng, GAO Shi-qiao, IN Lei
doaj  

Resonance frequency measurement to identify stiffness variations based on photoacoustic imaging

Biophysics and Physicobiology
Linear assumption on the level of stiffness in a tissue shows a significant correlation with disease. Photoacoustic imaging techniques that are non-contact by design have been developed in this study to detect differences in phantom (soft tissue ...
Ananta Kusuma Yoga Pratama, Andreas Setiawan, Rini Widyaningrum, Mitrayana   +3 more
doaj   +1 more source