Results 31 to 40 of about 746,464 (231)

Finite element model set-up of colorectal tissue for analyzing surgical scenarios [PDF]

open access: yes, 2017
Finite Element Analysis (FEA) has gained an extensive application in the medical field, such as soft tissues simulations. In particular, colorectal simulations can be used to understand the interaction with the surrounding tissues, or with instruments ...
Bici, Michele   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A fretting crack initiation prediction taking into account the surface roughness and the crack nucleation process volume

open access: yes, 2005
This paper presents an experimental study of the fretting crack nucleation threshold, expressed in terms of loading conditions, with a cylinder/plane contact.
Buffiere, Jean-Yves   +2 more
core   +3 more sources

A model for deformable roll coating with negative gaps and incompressible compliant layers [PDF]

open access: yes, 2003
A soft elastohydrodynamic lubrication model is formulated for deformable roll coating involving two contra-rotating rolls, one rigid and the other covered with a compliant layer. Included is a finite-strip model (FSM) for the deformation of the layer and
Gaskell, P.H.   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A multi-level interface model for damaged masonry [PDF]

open access: yes, 2013
The aim of the present work is to propose a new micro-mechanical model in the context of the deductive approach used to derive interface models. This model, based on a previous study introduced previously by A. Rekik and F.
Lebon, Frédéric   +3 more
core   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Analysis of axisymmetric bore-type foundation in respect of plastic deformation/Ašiai simetrinio gręžininio pamato analizė įvertinant plastines deformacijas

open access: yesJournal of Civil Engineering and Management, 1997
In order to design efficient foundations, it is necessary to know exact behaviour of them and surrounding soil under the load. At present various numerical methods [1–11] are used to determine such response.
Gintaras Bukotas, Rimantas Kačianauskas
doaj   +1 more source

Enhanced Strength and Ductility in Magnesium Matrix Composites Reinforced by a High Volume Fraction of Nano- and Submicron-Sized SiC Particles Produced by Mechanical Milling and Hot Extrusion [PDF]

open access: yes, 2019
In the present study, Mg nanocomposites with a high volume fraction (10 vol %) of SiC particles were fabricated by two approaches: mechanical milling and mixing, followed by the powder consolidation steps, including isostatic cold pressing, sintering ...
Fleck, Claudia   +3 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

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