Results 71 to 80 of about 134,646 (247)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Receiver Location Optimization for Heterogeneous S-Band Marine Transmitters in Passive Multistatic Radar Networks via NSGA-II

open access: yesSensors
Comprehensive maritime domain awareness is crucial for navigation safety, traffic management, and security surveillance. In the context of an increasingly complex modern electromagnetic environment, the disadvantages of traditional active single-station ...
Xinpeng Li   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

The cooperatives not agricultural as an alternative to the local development in the Isla de la Juventud

open access: yesCooperativismo y Desarrollo, 2017
The work has as objective to analyze the economic results - financial of the non agricultural cooperative “The Kitchen" as alternative for the local development in the Island of Youth, for that to leaned in the economic techniques - financial existent ...
Liudyana Dominguez Matos
doaj  

The Design Posture: A Collaborative Learning-By-Doing Approach

open access: yesDIID
In September 2021, Codesign Toscana1 organised a pop-up school animated by a concept implicitly present in many design-related debates and around which our practices as an interdisciplinary collective have developed over the last five years ...
Rita Duina, Marco Berni, Andrea Del Bono
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Effects of Dual-Operator Modes on Team Situation Awareness: A Non-Dyadic HMI Perspective in Intelligent Coal Mines

open access: yesApplied Sciences
Under the context of non-dyadic human–machine interaction in intelligent coal mines, this study investigates the impact of different dyadic collaboration modes on Team Situation Awareness (TSA).
Xiaofang Yuan   +3 more
doaj   +1 more source

Seeking discursive spaces for peace in media-sport narratives [PDF]

open access: yesConflict & Communication Online, 2009
Peace scholars have emphasized the importance of locating peace education outside of formal education or mainstream political rhetoric and into our daily interactions with media, religion, art, music, or sport.
Nancy K. Rivenburgh
doaj  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

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