Results 71 to 80 of about 15,500,515 (288)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Virginia Cooperative Extension Pledge Form
, 2014 This is a two page gift/pledge form in support of Virginia Cooperative ...
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Blind Estimation of Encoder and Interleaver Characteristics in a Non Cooperative Context
, 2003 In most digital transmission systems, the data stream is first encoded, then sent to an interleaver that rearranges the encoded symbols in order to provide protection against error bursts. In this paper, we consider analysis of an interleaved stream in a non cooperative context (i.e. military or spectrum surveillance application).
Burel, Gilles, Gautier, Roland
openaire +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Virginia Cooperative Extension Organizational Chart
, 2017 This document is an organizational chart of Virginia Cooperative Extension personnel.title from VCE publications page; document revised August ...
Jones, Edwin J.
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A hypothesis of coevolution between cooperation and responses to inequity
Frontiers in Neuroscience, 2011 Recent evidence demonstrates that humans are not the only species to respond negatively to inequitable outcomes which are to their disadvantage. Several species respond negatively if they subsequently receive a less good reward than a social partner for
Sarah F Brosnan, Sarah F Brosnan
doaj +1 more source
Deterministic Non-cooperative P Systems with Strong Context Conditions
, 2016 We continue the line of research of deterministic parallel non-cooperative multiset rewriting with control. We here generalize control, i.e., rule applicability context conditions, from promoters and inhibitors checking presence or absence of certain object up to some bound, to regular and even stronger predicates, focusing at predicates over ...
Alhazov, Artiom, Freund, Rudolf
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Virginia Cooperative Extension Organizational Chart
, 2019 This document is an organizational chart of Virginia Cooperative Extension personnel.title from VCE publications page; document revised July ...
Jones, Edwin J.
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source