Results 21 to 30 of about 156,008 (242)
Non-covalent interaction between polyubiquitin and GTP cyclohydrolase 1 dictates its degradation. [PDF]
PLoS ONE, 2012 GTP cyclohydrolase 1 (GTPCH1) is the rate-limiting enzyme in the de novo synthesis of tetrahydrobiopterin (BH4). GTPCH1 protein degradation has been reported in animal models of several diseases, including diabetes mellitus and hypertension. However, the
Yu Zhao, Huaiping Zhu, Ming-Hui Zou
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Alignment of non-covalent interactions at protein-protein interfaces. [PDF]
PLoS ONE, 2008 BACKGROUND: The study and comparison of protein-protein interfaces is essential for the understanding of the mechanisms of interaction between proteins.
Hongbo Zhu +3 more
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Non-covalent interactions descriptor using experimental electron densities [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2011 Non covalent interactions (NCI) play a crucial role in biology (protein-drug recognition) and in the design of new materials (selfassembly). A novel electron density (ED) based descriptor of non covalent interaction was proposed in 2010 by Johnson et al.[1].
G. Saleh +3 more
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Investigation of atomic level patterns in protein--small ligand interactions. [PDF]
PLoS ONE, 2009 BACKGROUND: Shape complementarity and non-covalent interactions are believed to drive protein-ligand interaction. To date protein-protein, protein-DNA, and protein-RNA interactions were systematically investigated, which is in contrast to interactions ...
Ke Chen, Lukasz Kurgan
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Physical networks from entropy-driven non-covalent interactions [PDF]
Nature Communications, 2021 AbstractPhysical networks typically employ enthalpy-dominated crosslinking interactions that become more dynamic at elevated temperatures, leading to network softening. Moreover, standard mathematical frameworks such as time-temperature superposition assume network softening and faster dynamics at elevated temperatures.
Anthony C. Yu +5 more
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Foods, 2022 The interaction between polyphenols and polysaccharides plays an important role in increasing the turbidity stability of fruit juice and improving unpleasant sensory experiences.
Xuan Zhang +9 more
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Supramolecular MaterialsPlastic recycling, especially the recycling of thermosets, is a crucial step towards improving waste management and achieving economic recycling. Here, a method utilizing non-covalent supramolecular interactions and synergistic hyperbranched structures ...
Yueran He +5 more
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Theoretical Investigation on Non-Covalent Interactions [PDF]
Crystals, 2022 This editorial is dedicated to announcing the Special Issue “Theoretical investigation on non-covalent interactions” of Crystals. The Special Issue covers the most recent progress in the rapidly growing fields of data science, artificial intelligence, and quantum and computational chemistry in topics relevant to the problem of theoretical investigation
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Preventing disulfide bond formation weakens non-covalent forces among lysozyme aggregates. [PDF]
PLoS ONE, 2014 Nonnative disulfide bonds have been observed among protein aggregates in several diseases like amyotrophic lateral sclerosis, cataract and so on. The molecular mechanism by which formation of such bonds promotes protein aggregation is poorly understood ...
Vijay Kumar Ravi +4 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source