Results 41 to 50 of about 109,235 (268)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Electromagnetic induction in non-uniform domains

, 2010
Kinematic simulations of the induction equation are carried out for different setups suitable for the von-K\'arm\'an-Sodium (VKS) dynamo experiment. Material properties of the flow driving impellers are considered by means of high conducting and high ...
Gerbeth, G., Giesecke, A., Guermond, J. -L., Luddens, F., Léorat, J., Nore, C., Stefani, F.   +6 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

On the solvability of a boundary value problem for a two-dimensional system of Navier-Stokes equations in a cone

Қарағанды университетінің хабаршысы. Математика сериясы
Due to the fact that the Navier-Stokes equations are involved in the formulation of a large number of interesting problems that are important from an applied point of view, these equations have been the object of attention of mechanics, mathematicians ...
M.T. Jenaliyev, A.M. Serik, M.G. Yergaliyev   +2 more
doaj   +1 more source

Dynamics of wave equations with moving boundary [PDF]

, 2017
This paper is concerned with long-time dynamics of weakly damped semilinear wave equations defined on domains with moving boundary. Since the boundary is a function of the time variable the problem is intrinsically non-autonomous.
Ma, To Fu, Marín Rubio, Pedro, Surco Chuño, Christian Manuel   +2 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Pattern formation on the surface of cationic-anionic cylindrical aggregates

, 2005
Charged pattern formation on the surfaces of self--assembled cylindrical micelles formed from oppositely charged heterogeneous molecules such as cationic and anionic peptide amphiphiles is investigated.
A. Ben-Naim, D. R. Nelson, K. L. Niece, M. Olvera de la Cruz, P. M. Chaikin, R. P. Feynman, S. A. Brazovskii, Y. S. Velichko   +7 more
core   +1 more source

On a Problem Connected with Navier-stokes Equations in Non Cylindrical Domains

Journal of Mathematics and Statistics, 2005
Summary: We showed the existence of weak solutions of equations that represent flows of a non-homogeneous viscous incompressible fluids in a non cylindrical domain in \(\mathbb R^3\). The classical Navier-Stokes equation is a particular case of the equations here considered.
Limaco, J., De Menezes, S. B., Vaz, C., Montenegro, J. F   +3 more
openaire   +2 more sources

Biopsychosocial determinants of hand function and its trajectories over five years in patients with hand osteoarthritis

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to investigate hand function trajectories over 5 years in primary hand osteoarthritis. Additionally, determinants of baseline and longitudinal hand function were assessed. Methods 538 patients with both baseline and 5‐year study visits were analyzed.
Annemiek V.E.M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source

Minimal surfaces and entanglement entropy in anti-de Sitter space

, 2014
According to Ryu and Takayanagi, the entanglement entropy in conformal field theory (CFT) is related through the AdS/CFT correspondence to the area of a minimal surface in the bulk.
Krtous, Pavel, Zelnikov, Andrei
core   +1 more source