Results 41 to 50 of about 279,309 (306)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Knowledge-based support in Non-Destructive Testing for health monitoring of aircraft structures [PDF]

open access: yes, 2012
Maintenance manuals include general methods and procedures for industrial maintenance and they contain information about principles of maintenance methods.
Kamsu-Foguem, Bernard
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Artificial intelligence techniques for the automatic interpretation of data from non-destructive testing

open access: yes, 2006
This paper attempts to summarise the findings of a largenumber of research papers deploying artificial intelligence(AI) techniques for the automatic interpretation of data from non-destructive testing (NDT).
Yella, S   +7 more
core   +1 more source

Fiber-optic annular detector array for large depth of field photoacoustic macroscopy

open access: yesPhotoacoustics, 2017
We report on a novel imaging system for large depth of field photoacoustic scanning macroscopy. Instead of commonly used piezoelectric transducers, fiber-optic based ultrasound detection is applied.
Johannes Bauer-Marschallinger   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Monitoring and analysing oil condition to generate maintenance savings: a case study in a CNG engine powered urban transport fleet [PDF]

open access: yes, 2013
The authors from Universitat Politecnica de Valencia wish to thank Spanish Grant TRA2008-06508 from Ministerio de Ciencia e Innovacion - Direccion General de Investigacion for supporting this work.
Olmeda, P.,   +8 more
core   +1 more source

Scanning Tunneling Microscopy of Intermediate Transformation Structures in Electric Arc Surfacing Modified with Titanium Carbonitrides on Pipe Steel

open access: yesCrystals, 2023
In the present paper, the structure of electric arc coatings modified with nanodispersed titanium carbonitride additives on low-carbon pipe steel is studied using optical, scanning tunneling, and transmission electron microscopy.
Kuznetsov Pavel   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Cloud-based non-destructive characterization

open access: yes, 2023
Cloud services have grown in popularity; businesses, organizations, industries, and academic institutions use cloud services such as Cloud Non-destructive Characterization Testing (CNDCT), also known as Cloud Testing (CT).
Heidari,A., Otsuki,A., Navimipour,N.J.
core   +1 more source

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