Results 71 to 80 of about 866,117 (283)

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

Advanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du, Yudi Ren, Qiaoqiao Meng, Peng Wei, Ruyu Zhu, Junjie Bao, Ye Yang, Shuo Yan, Chaorong Yue, Xueying Zhu, Shuo Cao, Chunxia Hao, Wei Sun, Yongli Song, Xihe Li, Zhimin Wu, Siqin Bao, Yanglin Chen   +17 more
wiley   +1 more source

Une ponction dans le fonds Paul Guadet : les plans de pose du revêtement de l’Hôtel Carnot, 1906-1908

Les Cahiers de la Recherche Architecturale, Urbaine et Paysagère, 2020
Previously only realised in infrastructural projects and industrial buildings, the introduction of reinforced-concrete frames in domestic and commercial architecture during the first years of the twentieth century in Paris required new solutions for the ...
Valentin Gillet
doaj   +1 more source

Choice of Ownership Structure and Firm Performance: Evidence from Estonia [PDF]

, 2003
In this paper we use rich panel data for a representative sample of Estonian enterprises to analyse diverse issues related to the determinants of ownership structures and ownership changes after privatisation.
Jones, Derek C., Kalmi, Panu, Mygind, Niels   +2 more
core   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Policy Volatility and Normative Challenges: American Engagement in Syria (2011–2024) and the Reconfiguration of Global Governance

Society
The Syrian conflict, ongoing since 2011, has revealed the volatility of American foreign policy and raised critical normative questions for global governance. This article examines the trajectory of U.S.
Wajid Fauzi, Ida Rochani Adi, Hindun Hindun   +2 more
doaj   +1 more source

Distortionary Domestic Taxation and Pareto-Efficient International Trade [PDF]

This paper characterises the domestic tax systems which yield Pareto-efficient outcomes for a two-country world economy in which each country uses distortionary taxes.
Jeremy Edwards, Ronnie Schöb
core  

H⁺ Exchange‐Driven ppb‐Level and High‐Selective Formaldehyde Detection at Room Temperature for Environmental and Clinical Applications

Advanced Science, EarlyView.
This article presents an innovative room‐temperature formaldehyde sensor based on H⁺ exchange method, achieving ppb‐level detection limit and exceptional selectivity. The study highlights its practical potential for real‐time environmental monitoring and clinical diagnostic applications.
Lubing Cai, Mengyang Pang, Zhaosong Liu, Yanfei Li, Jiani Li, Zhaorui Zhang, Fengshuang Zheng, Chao Li, Ang Zheng, Xuemin Zhang   +9 more
wiley   +1 more source

International Listing as a Means to Mobilize the Benefits of Financial Globalization: Micro-Level Evidence from China [PDF]

, 2009
This paper proposes a micro-level framework to account for how firms in developing economies overcome domestic institutional constraints. It illustrates that the mechanisms enabling those firms to benefit from financial globalization are more complex ...
Sun, Laixiang, Tobin, Damian
core   +1 more source

Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

Advanced Science, EarlyView.
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang, Xiaoran Lu, Sunan Li, Tao Wang, Iqbal Ahmad, Yong‐Hui Zheng   +5 more
wiley   +1 more source

The risks of investing in the real estate markets of the asian region [PDF]

, 2001
The Asian region has become a focus of attention for investors in recent years. Due to the strong economic performance of the region, the higher expected returns in the area compared with Europe and the USA and the additional diversification benefits ...
Lee, Stephen
core