Results 41 to 50 of about 10,958,315 (276)

Investigations on vehicle non-exhaust particle emissions: real-time measurements

International Journal of Environmental Science and Technology, 2022
Despite the potentially harmful effects on health and environmental impacts correlated with non-exhaust emissions (e.g., brake, tire and road wear and resuspension), but very limited environmental research studies have measured the contribution of vehicle non-exhaust emissions in real-world measurements and at different road segment types.
Belkacem, Ines, Helali, Ali, Khardi, Salah, Slimi, Khalifa   +3 more
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Characterising and Differentiating Non-Exhaust Airborne Nanoparticle Sources in Urban Traffic and Background Environments

Atmosphere
The contribution of non-exhaust emissions (NEEs) to particle number concentration (PNC) remains insufficiently quantified, particularly across different urban environments.
Yingyue Wei, George Biskos, Prashant Kumar   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Differentiated impact of low-exhaust-emission vehicles on NO $$_\text {2}$$ 2 and particle concentrations in the Paris region

European Transport Research Review
Higher concentrations of air pollutants, such as nitrogen dioxide (NO $$_\text {2}$$ 2 ) and particulate matter (PM), are observed in streets compared to the urban background.
Thibaud Sarica, Christophe Chaillou, Yelva Roustan, Clément Larrieu, Salah-Eddine Wali, Karine Sartelet   +5 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Investigations into the Performance and Emission Characteristics of a Biodiesel Fuelled CI Engine under Steady and Transient Operating Conditions [PDF]

The stringent emission laws, the depletion of petroleum reserves and the relation of fuels with politics have forced the world to find alternatives to fossil fuels.
Tesfa, Belachew Chekene
core   +3 more sources

Variation of Engine Performance and Emissions using Ethanol Blends. [PDF]

The limited fossil fuel resources along with the increased public concerns about pollution levels have increased the need for alternative fuels for use in internal combustion engines.
Abuhabaya, Abdullah, Fieldhouse, John D.
core   +4 more sources