Results 41 to 50 of about 10,724,726 (280)

Investigations on vehicle non-exhaust particle emissions: real-time measurements

open access: yesInternational Journal of Environmental Science and Technology, 2022
Despite the potentially harmful effects on health and environmental impacts correlated with non-exhaust emissions (e.g., brake, tire and road wear and resuspension), but very limited environmental research studies have measured the contribution of vehicle non-exhaust emissions in real-world measurements and at different road segment types.
Belkacem, Ines   +3 more
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

The impact of thermal status on emissions of a non-road diesel engine equipped with aftertreatment system under transient operation

open access: yesCase Studies in Thermal Engineering, 2022
The current study investigates the influence of hot and cold start on the emissions of a non-road diesel engine with an after-treatment system. The emissions were studied by experimental measurements on an engine during non-road transient operating ...
Renhua Feng   +5 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Winter emission factors of ultrafine total and solid particle numbers and PM2.5 near a major arterial road in Tokyo

open access: yesAtmospheric Environment: X
Road-traffic particulate emissions are regulated by limits expressed as emission factors per driving distance. However, these limits are difficult to compare directly to atmospheric concentrations.
Hiroyuki Hagino
doaj   +1 more source

Effects of Reactive Species Produced by Electrolysis of Water Mist and Air through Non-Thermal Plasma on the Performance and Exhaust Gas of Gasoline Engines

open access: yesMolecules, 2022
Countries are paying increasing attention to environmental issues and are moving towards the goal of energy saving and carbon reduction. This research presents a method to analyse the effects of the use of non-thermal plasma (NTP) and water injection (WI)
Chia-Hsin Hsieh   +3 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Effect of Cylinder-by-Cylinder Variation on Performance and Gaseous Emissions of a PFI Spark Ignition Engine: Experimental and 1D Numerical Study

open access: yesApplied Sciences, 2021
Combustion stability, engine efficiency and emissions in a multi-cylinder spark-ignition internal combustion engines can be improved through the advanced control and optimization of individual cylinder operation.
Luigi Teodosio   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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