Results 71 to 80 of about 388,952 (265)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Operationalization-Based Modeling of Software Non-Functional Requirement Relationships

Proceedings of the International Florida Artificial Intelligence Research Society Conference
Software Non-Functional Requirements (NFRs), also known as Quality Attributes (QAs), such as security, performance, and usability, play a critical role in shaping software architecture.
Unnati Shah, Siba Mishra
doaj  

On the Effectiveness of Zero-Shot and Few-Shot Pretrained Language Models for Software Requirement Classification

IEEE Access
Accurate classification of software requirements, particularly distinguishing between fun- ctional and non-functional requirements, is essential for enabling traceability, guiding system design, and ensuring project success.
Md Shafikuzzaman, Md Rakibul Islam, Shuaib Zaman, Andrew Ma, Anwarul Islam Sifat   +4 more
doaj   +1 more source

Endovascular control of haemorrhagic urological emergencies: an observational study

BMC Urology, 2006
Background Transarterial embolisation (TAE) is an effective method in control of haemorrhage irrespective of the nature of urological emergency. As the technique and technology have evolved, it is now possible to perform highly selective embolisation ...
Thorpe Peter, Nabi Ghulam, Somani Bhaskar K, McClinton Sam   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Design of safety critical and control systems of Nuclear Power Plants using Petri nets

Nuclear Engineering and Technology, 2019
Non-functional requirements plays a critical role in designing variety of applications domain ranges from safety-critical systems to simple gaming applications.
Pooja Singh, Lalit Kumar Singh
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Group Structure as a Foundation for Entropies

Entropy
Entropy can signify different things. For instance, heat transfer in thermodynamics or a measure of information in data analysis. Many entropies have been introduced, and it can be difficult to ascertain their respective importance and merits.
Henrik Jeldtoft Jensen, Piergiulio Tempesta   +1 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source