Results 81 to 90 of about 655,442 (335)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A Reflection on First Nations in their Boreal Homelands in Ontario: Between a Rock and a Caribou

open access: yesConservation & Society, 2015
This article provides some thoughts on the impacts of the conservation vs development paradigm on First Nations, as it has played out in the Canadian Boreal Forest Agreement and the Far North Act in northern Ontario, Canada.
M A Smith
doaj   +1 more source

NGO impact on ensuring the quality of higher education in departmental HEIs

open access: yesУніверситети і лідерство, 2020
The process of higher education quality assurance is a strategic priority for the development of higher education in Ukraine. To meet the EHEA standards in the sphere of higher education for the Ukrainian HEIS to cooperate with European ones; the ...
Kateryna Tryma, Natalia Salnikova
doaj   +1 more source

Lessons for Co-management: Experiences from the Fisheries Management Science Programme (FMSP) [PDF]

open access: yes, 2006
The aim of this document is to communicate lessons for fisheries co-management that have emerged from a series of projects undertaken by the DFID Fisheries Management Science Programme (FMSP).
Charlotte Howard, Robert Arthur
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Role of non-governmental organisations in operations research in low-resource countries

open access: yesThe Lancet Global Health, 2014
Background: Research partnerships among practitioners, researchers, and affected communities are increasingly seen as important vehicles for translating findings to operational strategies.
Dr. Florence Nyangara, PhD
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Non-governmental organisations and foundations

open access: yes, 2023
Defining non governmental organizations (NGOs) and foundations, the entry outlines a global picture of the non-profit sector, emphasising the activities privileged in each major region through the analysis of the actions of NGOs and foundations. Then it examines various experiences and trajectories of these organizations' development at the local and ...
openaire   +2 more sources

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