Results 51 to 60 of about 392,989 (308)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Journal of MultiDisciplinary Evaluation, 2008 The five evaluation criteria from the Development Assistance Committee of the Economic Cooperation and Development (OECD/DAC) have been a strong foundation for international development evaluation since 1991. They have been the most prominent and widely
Thomaz Chianca
doaj +1 more source
International Journal of Supply Chain and Logistics, 2019 Purpose: The purpose of the study was to assess the influence of supplier evaluation criteria on procurement performance of non-governmental organizations in Kenya with an aim of making recommendations on proper use of supplier evaluation.Methodology: This research study adopted a descriptive research design approach.
URBANUS KIOKO MUTISO, Dr. GEORGE OCHIRI
openaire +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
HIV/AIDS Policy-Making in Iran: Part 2- from Formulation to Evaluation [PDF]
Taṣvīr-i salāmat, 2018 Background and Objectives: Achieving an appropriate policy needs an in-depth and comprehensive understanding of policy-making process. This study aimed to analyze HIV/AIDS policy-making process in Iran. Material and Methods: This is a qualitative/
Rahim Khodayari Zarnaq +2 more
doaj
Effectiveness criteria of ngos performance (by the example of the student’s government) [PDF]
, 2015 The role of non-governmental and non-profit organizations rise permanently in Ukraine. They role is to protect human rights and realize their interests.
Pavlenko, D.V.
core
Innovative public governance through cloud computing: Information privacy, business models and performance measurement challenges [PDF]
, 2014 Purpose: The purpose of this paper is to identify and analyze challenges and to discuss proposed solutions for innovative public governance through cloud computing.
Irani, Z, Lee, H, Tsohou, A
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source