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ApoB versus non-HDL-C: What to do when they disagree

Current Atherosclerosis Reports, 2009
The high correlation between apolipoprotein B (apoB) and non-high-density lipoprotein cholesterol (non-HDL-C) is the chief argument employed against introducing apoB into clinical practice. However, high correlation does mean that non-HDL-C and apoB will often yield similar clinical information. Nevertheless, the critical issue is not how often the two
Allan, Sniderman   +2 more
openaire   +2 more sources

ApoB, LDL-C, and non-HDL-C as markers of cardiovascular risk

Journal of Clinical Lipidology
Conventional statistical approaches are not designed to compare highly correlated variables such as low-density lipoprotein cholesterol (LDL-C), non-high density lipoprotein cholesterol (non-HDL-C), and apolipoprotein B (apoB). Discordance analysis was designed to overcome this limitation by creating groups in which the predictions of 2 markers differ ...
Daniel Sehayek   +9 more
openaire   +3 more sources

In diabetes, some statins reduce non–HDL-C better than others vs. placebo

Annals of Internal Medicine, 2022
Hodkinson A, Tsimpida D, Kontopantelis E, et al. Comparative effectiveness of statins on non-high density lipoprotein cholesterol in people with diabetes and at risk of cardiovascular disease: systematic review and network meta-analysis. BMJ. 2022;376:e067731. 35331984.
openaire   +2 more sources

Non-HDL-C is a Better Predictor for the Severity of Coronary Atherosclerosis Compared with LDL-C

Heart, Lung and Circulation, 2016
Recent guidelines recommended both low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) are the primary target of lipid modulating therapy. However, which lipid measure is most closely related to the severity of coronary atherosclerosis has not yet been assessed.We studied 1757 consecutive subjects ...
Yan, Zhang   +10 more
openaire   +2 more sources

Association of non-HDL-C and risk of incident hypertension

Abstract Background The study aimed to investigate the association between non-high-density lipoprotein cholesterol (non-HDL-C) and risk of incident hypertension, especially concerning the association of different levels of low-density lipoprotein cholesterol (LDL-C) and non-HDL-C with risk of ...
Xinxin He   +13 more
openaire   +1 more source

An evidence-based analysis of the National Lipid Association recommendations concerning non-HDL-C and apoB

Journal of Clinical Lipidology, 2016
The National Lipid Association (NLA) selected non-HDL-C as its prime index of the cardiovascular risk associated with the apoB lipoproteins. ApoB was recommended only as an optional secondary target after low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (HDL-C) targets were achieved.The aims of this analysis were
Allan D, Sniderman   +3 more
openaire   +2 more sources

Changes in triglyceride, HDL-C, and non-HDL-C levels in patients with acute coronary syndrome

Wiener klinische Wochenschrift, 2016
Changes in high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels have been linked to residual cardiovascular risk, whereas non-HDL-C levels have been shown to be more predictive of cardiovascular risk than are low-density lipoprotein cholesterol (LDL-C) levels. We aimed to investigate the impact of HDL-C, TG, and non-HDL-C levels on
Péter, Koncsos   +6 more
openaire   +2 more sources

Lipoprotein remnants and dense LDL are associated with features of unstable carotid plaque: A flag for non-HDL-C

Atherosclerosis, 2013
We investigated the association between cholesterol across the LDL density range and in the VLDL and IDL particles with the prevalence of inflammatory cells in plaques of patients with severe carotid artery stenosis.Forty-five patients undergoing carotid endarterectomy were studied.
ZAMBON, ALBERTO   +5 more
openaire   +3 more sources

HDL in the 21st Century: A Multifunctional Roadmap for Future HDL Research

Circulation, 2021
Alan Remaley   +2 more
exaly  

The Advantages of Using Non–HDL-C in the Diagnosis and Treatment of Dyslipidemia

Archives of Internal Medicine, 2002
Carlos A. Aguilar-Salinas   +2 more
openaire   +1 more source

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