Results 121 to 130 of about 10,191,062 (296)

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Cyanogenic Compounds, Physicochemical Parameters and Metals in Water From Cassava Processing Areas: A Study in the Brazilian Amazon, Using Multivariate Analysis

Environmental Toxicology, EarlyView.
ABSTRACT This study evaluated the water quality of artesian wells and effluents generated in cassava processing in a rural area of Bragança, Pará, with emphasis on physicochemical parameters, multielement composition, and cyanogenic compounds. The well water presented specific nonconformities, highlighting pH values below the recommended level and high
Alana Coêlho Maciel, Mariane Gama Nabiça, Luciana Pinheiro Santos, Thiago de Melo e Silva, Elivaldo Nunes Modesto Junior, Heronides Adonias Dantas Filho, Charles Miller de Souza Borges, Kelly das Graças Fernandes Dantas, Simone de Fátima Pinheiro Pereira, Ivan Carlos da Costa Barbosa, Beni Jequicene Mussengue Chaúque, Rosinelson da Silva Pena, Nayara Macêdo Peixoto Araújo, Alessandra Santos Lopes   +13 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

A Hodgkin lymphoma pulmonális megjelenési formái

, 2015
Bevezetés: A Hodgkin lymphoma korunk egyik legsikeresebben kezelhető onkohematológiai kórképe. Az extranodalis kiterjedés viszonylag ritka, a tüdő érintettsége a betegek 5,9-11,6%-ánál fordul elő, és általában előrehaladott betegségben észleljük ...
Szemes, Katalin
core  

Intraoral Swelling: A Rare Case Report with Diagnostic Perplexity

Journal of Indian Academy of Oral Medicine and Radiology
Non-Hodgkin lymphomas are malignant tumor that arises from the lymphoreticular system. Anaplastic large cell lymphoma (ALCL) is a type of non-Hodgkin lymphoma distinguished by the proliferation of pleomorphic large lymphoid cells expressing CD30 antigen.
Vikram Singh, Pratiksha Hada, Sakshi Sharma, Shivam Dubey   +3 more
doaj   +1 more source

Building a precision therapeutics program at a tertiary care children's hospital

Pediatric Investigation, EarlyView.
Luke Hamilton, Heidi Trinkman, Diana Carrasco, Kaitlin Smith, Kelly Vallance, Alejandra Dominguez, Danielle Miller, Megan Gibbs, Anish Ray   +8 more
wiley   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

VIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf, Yara Mashal, Afeefa Rao, Nasar Ata, Arun K. Iyer, Farhan Shah   +5 more
wiley   +1 more source

Extramedullary Plasmacytoma of Base of Tongue: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Identifying extramedullary plasmacytoma originating from the base‐of‐tongue, in order to evaluate its prevalence, characteristics, management, and treatment within the broader spectrum of head and neck extramedullary plasmacytoma.
Ori Cohen Michael, Ameen Biadsee, Firas Kassem, Matan Katz, Osnat Jarchowsky‐Dolberg, Benny Nageris, Tomer Boldes   +6 more
wiley   +1 more source

3q27 rearrangements in non Hodgkin lymphoma - t(3;Var)(q27;Var) in non Hodgkin lymphoma

, 2000
Review on 3q27 rearrangements in non Hodgkin lymphoma - t(3;Var)(q27;Var) in non Hodgkin lymphoma, with data on clinics, and the genes ...
Huret, JL, Cuneo, A
core   +1 more source