Results 161 to 170 of about 14,052 (271)

Structured Inequality, Uncertain Lifespans: Demographic Perspectives on Predicting Individual‐Level Longevity

open access: yesPopulation and Development Review, EarlyView.
Abstract There are striking disparities in life expectancy across sociodemographic groups in the United States, shaped by structural forces such as racism, class inequality, and policy environments. To what extent do sociodemographic characteristics structure—or fail to structure—individual lifespans? Using U.S.
Casey F. Breen, Nathan Seltzer
wiley   +1 more source

Repelled Point Processes With Application to Numerical Integration

open access: yesScandinavian Journal of Statistics, EarlyView.
ABSTRACT We look at Monte Carlo numerical integration from a stochastic geometry point of view. While crude Monte Carlo estimators relate to linear statistics of a homogeneous Poisson point process (PPP), linear statistics of more regularly spread point processes can yield unbiased estimators with faster‐decaying variance, and thus lower integration ...
Diala Hawat   +3 more
wiley   +1 more source

Emergence of Continents Stabilized the Bioavailability of Boron

open access: yesTerra Nova, EarlyView.
ABSTRACT Boron is an essential element for the development of life on Earth; borates stabilize ribose in prebiotic reactions and facilitate metabolism in higher plants. There is, however, a relatively narrow surface boron concentration range over which borates stabilize and serve as a micronutrient rather than a toxin.
Brendan V. Dyck, Jon Wade
wiley   +1 more source

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger   +4 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

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