Results 141 to 150 of about 1,031,153 (395)
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie+8 more
wiley +1 more source
Distribution of the Human Rh0(D) Antigen in the Red Cells of Non-Human Primates [PDF]
S. P. Masouredis+2 more
openalex +1 more source
A Non-Human Primate Model of Severe Pneumococcal Pneumonia
Rationale Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and infectious death in adults worldwide. A non-human primate model is needed to study the molecular mechanisms that underlie the development of severe pneumonia ...
L. Reyes+14 more
semanticscholar +1 more source
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo+20 more
wiley +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source
Degeneration of neurons and circuits across the striatum shows stereotyped time-course and spatial topography patterns that are distinct for Huntington's disease, Parkinson's disease, or the Tauopathies. These patterns of neurodegeneration in humans have
Natalia López-González del Rey+1 more
doaj
Studies of uptake of the bretylium analogue, iodobenzyltrimethylammonium iodide, by non‐primate, monkey and human hearts. [PDF]
E.R. Carr+3 more
openalex +1 more source
This study examines how the human hippocampus encodes visual memory categories. By decoding spiking activity from CA3 and CA1 neurons using an interpretable model, it reveals that category‐specific representations emerge from distributed temporal coding.
Xiwei She+17 more
wiley +1 more source
Primate phylogeny: molecular evidence for a pongid clade excluding humans and a prosimian clade containing tarsiers [PDF]
Interpretations of molecular data by the modern evolution theory are often sharply inconsistent with paleontological results. This is to be expected since the theory is only true for microevolution and yet fossil records are mostly about macroevolution.
Shi Huang
core +1 more source
Second Inter-American Conference on Conservation and Utilization of American Non-Human Primates in Biomedical Research / The Primatological Society of India [PDF]
T. C. Anand Kumar
openalex +1 more source