Diabetic wound healing is blocked by persistent inflammation and oxidative stress. Bioactive substances like growth factors and Hsts promote repair but lack long‐term stability. Herein, a platelet membrane‐coated nanoparticle system (PNP) is proposed to achieve enhanced retention of aggregation‐induced emissive (AIE) molecular‐modified Hst1 (Hst1‐AIE ...
Xiaoxuan Lei+9 more
wiley +1 more source
Non-Human Primate Models of Orthopoxvirus Infections
Smallpox, one of the most destructive diseases, has been successfully eradicated through a worldwide vaccination campaign. Since immunization programs have been stopped, the number of people with vaccinia virus induced immunity is declining.
Anne Schmitt+2 more
doaj +1 more source
Intérêts et limites de l'approche moléculaire pour aborder la biogéographie et la spéciation : l'exemple de quelques Mammifères d'Afrique tropicale [PDF]
We attempted to test biogeographic hypotheses proposed for the evolution of tropical faunas using mitochondrial DNA sequences of selected African mammalian taxa (Insectivora, Rodentia and Primates). 1/ we constructed a molecular phylogeny of taxa in order to ascertain their monophyly and calibrate a molecular clock; 2/ we analysed and compared the ...
arxiv
Characterization of non-human primate antisera to acute lymphoblastic leukemia (ALL): evidence for unique antigen(s) on childhood ALL of "T" phenotype [PDF]
Thalachallour Mohanakumar+4 more
openalex +1 more source
Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky+3 more
wiley +1 more source
Network nestedness in primates: a structural constraint or a biological advantage of social complexity? [PDF]
This study investigates the prevalence and implications of nestedness within primate social networks, examining its relationship with cognitive and structural factors. We analysed data from 51 primate groups across 21 species, employing network analysis to evaluate nestedness and its correlation with modularity, neocortex ratio, and group size. We used
arxiv
A predictive structural model of the primate connectome [PDF]
Anatomical connectivity imposes strong constraints on brain function, but there is no general agreement about principles that govern its organization. Based on extensive quantitative data we tested the power of three models to predict connections of the primate cerebral cortex: architectonic similarity (structural model), spatial proximity (distance ...
arxiv
Inhibition of cellular activation of retroviral replication by CD8+ T cells derived from non-human primates [PDF]
Jonathan D. Powell+6 more
openalex +1 more source
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska+2 more
wiley +1 more source
Oxytocin and vasopressin in non-human primates
Author(s): Ragen, BJ; Bales, KL | Abstract: Neuroanatomy of OT and AVP in non-human primates OT and AVP immunoreactive cells and fibers in the brain, spinal cord, and pineal gland Atunes and Zimmerman (1978) performed one of the first studies using antisera to AVP, OT, and neurophysins to visualize the OT and AVP system in the hypothalamus of non-human
Ragen, Benjamin J, Bales, Karen L
openaire +3 more sources