Results 91 to 100 of about 1,363,663 (300)

Ideology and disease identity : the politics of rickets, 1929-1982 [PDF]

, 2013
How can we assess the reciprocal impacts of politics and medicine in the contemporary period? Using the example of rickets in twentieth century Britain, I will explore the ways in which a preventable, curable non-infectious disease came to have enormous ...
Apple, Arneil, Arneil, Benson, Berry, Bivins, British Paediatric Association, Carne, Chick, Dunnigan, Dunnigan, Dunnigan, Dunnigan, Ford, Ford, Ford, Ford, Frazer, Games, Grant, Heath, Hodgkin, Holmes, Hutt, Jameson, Kamminga, Kamminga, Lester, M'Gonigle, MacNalty, Magee, Marrack, McIntosh, McKay, Murcott, Orwell, Roberta Bivins, Robertson, Schwarz, Smerdon, Smith, Stanbury, Stewart, Swan, Walker, Webster, Webster, Webster, Webster, Whistler, Young   +50 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Cancer Transition in Japan since 1951 [PDF]

The overall trend of cancer mortality in Japan has been decreasing since the 1960s (age-standardized death rates for ages 30-69), though trends differ enormously among various forms of the disease.
John R. Wilmoth, Omer Gersten
core  

Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity [PDF]

, 2015
Correction of human myeloid cell function is crucial for the prevention of inflammatory and allergic reactions as well as leukaemia progression. Caffeine, a naturally occurring food component, is known to display anti-inflammatory effects which have ...
Abooali, Maryam, Berger, Steffen M., Casely-Hayford, Maxwell A., Fasler-Kan, Elizaveta, Gibbs, Bernhard F., Gonçalves Silva, Isabel, Prokhorov, Alexandr, Sumbayev, Vadim V., Yasinska, Inna M.   +8 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Non-infectious chronic blepharitis pharmacotherapy

Oftalʹmologiâ, 2014
Purpose: To evaluate the effectiveness of complex treatment included the eyelid hygiene in non-infectious chronic blepharitis patients.Methods: 50 non-infectious chronic blepharitis, meibomian gland dysfunction and dry eye patients (18‑46 years) were ...
S. N. Sakhnov, S. V. Yanchenko, A. S. Rudashova, A. V. Malyshev   +3 more
doaj   +3 more sources

Epidemic Characteristics and Influencing Factors of Bone and Joint Diseases among the Elderly Population [PDF]

Zhongguo quanke yixue
Background Given the increasing prevalence of the high incidence of bone and joint diseases in the elderly population, and significantly associated with higher mortality, more disability, decline in functional status and lower quality of life, this ...
GAO Yan, YANG Shuxian, FAN Lei, CHANG Liang, GAO Li, ZHANG Hanxue, LI Hui, KANG Kai
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The Impact of Nutrition and Fine Particulate Matter (PM2.5) on Inflammatory Responses in Individuals with Metabolic Syndrome: A Paired Case Study from Chiang Mai, Thailand

Toxics
Exposure to fine particulate matter (PM2.5) is linked to increased systemic inflammation, particularly in individuals with metabolic syndrome (MS). This study assessed the impact of nutrition and PM2.5 exposure on inflammatory markers in individuals with
Wason Parklak, Hataichanok Chuljerm, Sawaeng Kawichai, Puriwat Fakfum, Putita Jiraya, Praporn Kijkuokool, Wiritphon Khiaolaongam, Pakaphorn Ngamsang, Sakaewan Ounjaijean, Kittipan Rerkasem, Kanokwan Kulprachakarn   +10 more
doaj   +1 more source

INFECTIOUS AND NON-INFECTIOUS PERICARDITIS IN CHILDREN

Pediatria. Journal named after G.N. Speransky, 2017
Pericardial diseases in children are heterogeneous in nature and can be both isolated and part of the systemic pathology. Data on the epidemiology and etiology of pericardial disease are contradictory and depend on the hospital profile, patients' age and study aims. Objective of the research-to study modern structure of pericardial diseases in children,
Kantemirova M.G., Korovina O.A., Novikova Y.Y., Kiseleva I.N., Shokin A.A., Buzina N.V., Abramyan M.A., Lyapunova T.V., Lapshin A.A., Ovsyannikov D.Y., Koltunov I.E.   +10 more
openaire   +3 more sources