Results 61 to 70 of about 1,293,309 (243)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Non-infectious chronic blepharitis pharmacotherapy

Oftalʹmologiâ, 2014
Purpose: To evaluate the effectiveness of complex treatment included the eyelid hygiene in non-infectious chronic blepharitis patients.Methods: 50 non-infectious chronic blepharitis, meibomian gland dysfunction and dry eye patients (18‑46 years) were ...
S. N. Sakhnov, S. V. Yanchenko, A. S. Rudashova, A. V. Malyshev   +3 more
doaj   +3 more sources

Association Between Dietary Patterns and Lifestyle Habits with Vascular Inflammatory Responses in Individuals with Hypertension Living in PM_2.5-Polluted Areas: A Cross-Sectional Pilot Study in Chiang Mai Province, Thailand

Diseases
Background/Objectives: Exposure to fine particulate matter (PM2.5) is linked to increased cardiovascular risk, particularly in individuals with hypertension.
Wason Parklak, Kanokwan Kulprachakarn, Sawaeng Kawichai, Puriwat Fakfum, Putita Jiraya, Praporn Kijkuokool, Wiritphon Khiaolaongam, Hataichanok Chuljerm   +7 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Epidemic Characteristics and Influencing Factors of Bone and Joint Diseases among the Elderly Population [PDF]

Zhongguo quanke yixue
Background Given the increasing prevalence of the high incidence of bone and joint diseases in the elderly population, and significantly associated with higher mortality, more disability, decline in functional status and lower quality of life, this ...
GAO Yan, YANG Shuxian, FAN Lei, CHANG Liang, GAO Li, ZHANG Hanxue, LI Hui, KANG Kai
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The Impact of Nutrition and Fine Particulate Matter (PM2.5) on Inflammatory Responses in Individuals with Metabolic Syndrome: A Paired Case Study from Chiang Mai, Thailand

Toxics
Exposure to fine particulate matter (PM2.5) is linked to increased systemic inflammation, particularly in individuals with metabolic syndrome (MS). This study assessed the impact of nutrition and PM2.5 exposure on inflammatory markers in individuals with
Wason Parklak, Hataichanok Chuljerm, Sawaeng Kawichai, Puriwat Fakfum, Putita Jiraya, Praporn Kijkuokool, Wiritphon Khiaolaongam, Pakaphorn Ngamsang, Sakaewan Ounjaijean, Kittipan Rerkasem, Kanokwan Kulprachakarn   +10 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effectiveness of Triamcinolone Acetonide Injection for the Treatment of Non-infectious Intermediate and Posterior Uveitis

JLUMHS
OBJECTIVE: To assess the efficacy of posterior sub-tenon injection (PSTI) of Triamcinolone Acetonide (TA) in patients with Uveitis. METHODS: This prospective study was conducted from July 2022 to May 2023.
Iftikhar Ahmed, Rashid Hassan Alvi, Maaz Allah, Sarah Saleem, Muhammad Nizamuddin   +4 more
doaj   +1 more source