Results 1 to 10 of about 23,969 (235)

The effectiveness of adalimumab treatment for non-infectious uveitis [PDF]

Immunological Medicine, 2019
Uveitis, which is a major cause of blindness worldwide, is defined as intraocular inflammation that affects the iris, ciliary body, vitreous, retina and choroid.
Eiichi Hasegawa, Atsunobu Takeda, Nobuyo Yawata, Koh-Hei Sonoda   +3 more
doaj   +4 more sources

Epidemiology and Risk Factors in Non-infectious Uveitis: A Systematic Review

Frontiers in Medicine, 2021
Purpose: Non-infectious uveitis is a leading cause of vision loss in the developed world. The purpose of this systematic review is to investigate the epidemiology and risk factors of non-infectious uveitis over the last 50 years.Methods: A systematic ...
Katherine A. Joltikov, Ann-Marie Lobo-Chan   +1 more
doaj   +3 more sources

Exploring the involvement of the alternative complement pathway in non-infectious uveitis pathogenesis [PDF]

Frontiers in Immunology, 2023
PurposeNon-infectious uveitis is a complex disease characterized by intraocular inflammation of the uveal area and the leading cause of vision impairment and blindness in young people globally.
Prerna Kulshrestha, Prerna Kulshrestha, Pallavi Goel, Somasheila Murthy, Mudit Tyagi, Soumvaya Basu, Pratik Gogri, Inderjeet Kaur   +7 more
doaj   +2 more sources

Inflammatory cytokines as mediators of retinal endothelial barrier dysfunction in non‐infectious uveitis [PDF]

Clinical & Translational Immunology, 2023
Characterised by intraocular inflammation, non‐infectious uveitis includes a large group of autoimmune and autoinflammatory diseases that either involve the eye alone or have both ocular and systemic manifestations.
Lisia Barros Ferreira, Keryn A Williams, Giles Best, Cameron D Haydinger, Justine R Smith   +4 more
doaj   +2 more sources

Association between polycystic ovary syndrome and non-infectious uveitis [PDF]

Scientific Reports, 2023
Polycystic ovary syndrome (PCOS) is a common endocrine disease in young women. It has been reported that increased proinflammatory cytokines can induce systemic inflammation. However, the association between PCOS and uveitis remains elusive.
Chae Eun Lee, Nang Kyung Lee, Christopher Seungkyu Lee, Suk Ho Byeon, Sung Soo Kim, Seung Won Lee, Yong Joon Kim   +6 more
doaj   +2 more sources

Outcome of adalimumab monotherapy in paediatric non-infectious uveitis [PDF]

Pediatric Rheumatology Online Journal, 2023
Background Adalimumab in combination with other disease-modifying antirheumatic drugs (DMARD) such as methotrexate has a proven efficacy in the management of paediatric non-infectious uveitis.
DA Al-Julandani, NK Bagri, N Tsang, S Clarke, A Upadhyay, C Guly, AV Ramanan   +6 more
doaj   +2 more sources

Pharmacotherapy for non-infectious uveitis: spotlight on phase III clinical trials of locally injected or implanted therapeutics and systemic immunomodulatory drugs [PDF]

Journal of Ophthalmic Inflammation and Infection
Background Non-infectious uveitis is an uncommon eye condition, but an important cause of substantial vision impairment and blindness around the world.
Melissa K. Shields, Lisia Barros Ferreira, Syed B. Ali, Liana Dedina, Lyndell L. Lim, Eric B. Suhler, Justine R. Smith   +6 more
doaj   +2 more sources

Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II):a multicentre, double-masked, randomised, placebo-controlled phase 3 trial [PDF]

Lancet, The, 2016
Background Non-infectious uveitis is a potentially sight-threatening ocular disorder caused by chronic inflammation and its complications. Therapeutic success is limited by systemic adverse effects associated with long-term corticosteroid and ...
Brézin, Antoine P, Camez, Anne A, Cimino, Luca, Dick, Andrew D, Jaffe, Glenn J, Kron, Martina, Kurup, Shree Kumar, Kwatra, Nisha V, Merrill, Pauline T, Nguyen, Quan Dong, Pavesio, Carlos, Schlaen, Ariel, Sheppard, John, Song, Alexandra P, Tari, Samir, Van Calster, Joachim   +15 more
core   +5 more sources

Topical Anti-Inflammatory Agents for Non-Infectious Uveitis: Current Treatment and Perspectives

Journal of Inflammation Research, 2022
Balini Balasubramaniam,1 Yu Jeat Chong,2 Matthew Azzopardi,3 Abison Logeswaran,4 Alastair K Denniston1 1Ophthalmology Department, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2TH, UK; 2Birmingham ...
Balasubramaniam B, Chong YJ, Azzopardi M, Logeswaran A, Denniston AK   +4 more
doaj   +2 more sources

Prevalence and clinical characteristics of ocular sarcoidosis among non-infectious uveitis in a Chinese tertiary ophthalmic center: a retrospective observational study [PDF]

BMC Ophthalmology
Background The prevalence of ocular sarcoidosis (OS) varies across Asia and the application of the most recent revised diagnostic criteria has not yet been fully adopted. Thus, the prevalence of OS within the Chinese population remains uncertain.
Daquan He, Tianyu Tao, Xuening Peng, Jianjie Lv, Wenru Su   +4 more
doaj   +2 more sources