Results 111 to 120 of about 10,417,976 (225)

Ulceronecrotic Plaques, Patchy Scalp Alopecia and Visual Disturbance in a 46‐Year‐Old Man

International Journal of Dermatology, EarlyView.
ABSTRACT A 46‐year‐old incarcerated man with chronic hepatitis C infection and intravenous drug use presented with a rapidly progressive pruritic eruption involving the scalp, trunk, and limbs, accompanied by patchy scalp alopecia and bilateral panuveitis.
Alex Majri, Austen Anderson, Jeremy Ng, Nima Mesbah‐Ardakani   +3 more
wiley   +1 more source

The Effect of PTPN22 Polymorphism on Juvenile Idiopathic Arthritis Subtypes and Disease Activity in a Finnish Study Population

International Journal of Immunogenetics, EarlyView.
ABSTRACT Genetic factors that modulate immune regulation are increasingly recognised as contributors to the heterogeneity and clinical course of autoimmune diseases. Polymorphisms of protein tyrosine phosphatase non‐receptor type 22 (PTPN22) are associated with several autoimmune diseases.
Sonja Kvist, Johanna Teräsjärvi, Heidi Rahikkala, Jussi Mertsola, Milja Möttönen, Qiushui He   +5 more
wiley   +1 more source

A Population Pharmacokinetic Model of Gentamicin in Hospitalized Neonatal Foals

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Information on safe and effective gentamicin dosing in foals is limited. This study aimed to provide guidance regarding optimal dosing regimens by means of a population pharmacokinetic (popPK) model. Gentamicin plasma concentration of 290 samples from 72 hospitalized foals (≤ 14 days old), treated with intravenous (IV) gentamicin, was measured
Astrid J. van den Brom‐Spierenburg, Esther A. Winter, Mathijs J. P. Theelen, Ingeborg M. van Geijlswijk, Cornélie M. Westermann, Marianne M. Sloet van Oldruitenborgh‐Oosterbaan, Tim Florschütz, Johannes C. Vendrig, Esther W. Siegers, Kim de Graaf, Marc Cherlet, Mathias Devreese, Ronette Gehring   +12 more
wiley   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

HTLV screening and confirmatory testing among blood donors in São Paulo: A cross‐sectional study

Transfusion Medicine, EarlyView.
Abstract Introduction Human T‐cell lymphotropic virus types 1 and 2 (HTLV‐1/2) are transfusion‐transmissible retroviruses associated with severe diseases, and blood donor screening is mandatory in Brazil. Increasing HTLV‐related discard rates at our institution prompted this study to determine the prevalence and incidence of HTLV‐1/2 and to investigate
Suzete C. Ferreira, Anna S. Nishyia, Jerenice E. Ferreira, Claudia Di Lorenzo Oliveira, Cesar de Almeida‐Neto, Tila Fanciani, Katia C. Dantas, Juliana Derriga, Silvia Petrossi Gallo Polato, Nanci Salles, Vanderson Rocha, Alfredo Mendrone‐Junior   +11 more
wiley   +1 more source

New Insights Into Pathogenesis, Diagnostics, and Therapeutic Options for Canine Angiostrongylosis

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To provide a comprehensive overview of Angiostrongylus vasorum infection in dogs, with a particular emphasis on recent developments in the understanding of disease pathophysiology and an update on developments in diagnostic and therapeutic options.
Iris Elgueta, Daniel Lewis, Eric R. Morgan, Jenny Helm   +3 more
wiley   +1 more source

Integrative immunology identified interferome signatures in uveitis and systemic disease-associated uveitis

Frontiers in Immunology
IntroductionUveitis accounts for up to 25% of global legal blindness and involves intraocular inflammation, classifed as infectious or non-infectious. Its complex pathophysiology includes dysregulated cytokines, particularly interferons (IFNs).
Danielle Dias Munhoz, Dennyson Leandro M. Fonseca, Igor Salerno Filgueiras, Haroldo Dutra Dias, Helder I. Nakaya, Igor Jurisica, Igor Jurisica, Igor Jurisica, Hans D. Ochs, Hans D. Ochs, Lena F. Schimke, Luiz Vicente Rizzo, Otavio Cabral-Marques, Otavio Cabral-Marques, Otavio Cabral-Marques, Otavio Cabral-Marques, Otavio Cabral-Marques, Otavio Cabral-Marques   +17 more
doaj   +1 more source

Evaluation for endotoxin in intraocular materials used during phacoemulsification surgery using a recombinant factor C assay

Veterinary Ophthalmology, Volume 28, Issue 2, Page 481-485, March 2025.
Abstract Objective Cataract surgery remains the sole method to resolve blindness secondary to cataract formation. One complication includes fibrin web formation post‐operatively. This study aimed to investigate the presence of endotoxin within materials used during cataract surgery as a possible cause of fibrin web phenomenon. Methods Preservative‐free
Taylor A. Opgenorth, Eryn L. Opgenorth, J. Seth Eaton, Ellison Bentley   +3 more
wiley   +1 more source

Micropulse transscleral cyclophotocoagulation in canine glaucoma: A retrospective study evaluating sweep velocity

Veterinary Ophthalmology, Volume 28, Issue 2, Page 293-305, March 2025.
Abstract Objective To report preliminary results of MP‐TSCP in canine patients with glaucoma while evaluating sweep velocity, treatment efficacy, and safety utilizing standardized surgical parameters. Animal studied Client‐owned dogs that underwent MP‐TSCP at a veterinary referral hospital. Procedure Medical records of 19 eyes (14 dogs) treated with MP‐
Valeria Benitez‐Vera, Dineli Bras, Fabiano Montiani‐Ferreira   +2 more
wiley   +1 more source

Evaluation of photoactivated chromophore for keratitis–corneal cross‐linking (PACK‐CXL) in feline infectious keratitis—patient demographics, treatment protocols, risk factors, and treatment outcome: a retrospective study

Veterinary Ophthalmology, Volume 28, Issue 2, Page 330-340, March 2025.
Abstract Objectives To describe patient demographics and treatment protocols in a population of feline patients undergoing photoactivated chromophore for keratitis–corneal cross‐linking (PACK–CXL) as an adjunctive treatment for infectious keratitis.
Angelie K. Shukla, Malwina E. Kowalska, Kevin Arteaga, Manuela Crasta, Christopher Dixon, Frank Famose, Sonja Hartnack, Simon Anton Pot   +7 more
wiley   +1 more source