Results 121 to 130 of about 343,343 (306)

Human Rights in Non-International Armed Conflicts

, 2018
By analyzing the types of human rights’ violations in non-international armed conflicts, the evolution of human rights and humanitarian law, and the behavior of armed groups, the thesis will develop different ways - inspired by the work of the International Committee of the Red Cross and NGOs - for protecting the civilians’ basic rights in these ...
openaire   +2 more sources

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

The Law of Armed Conflict, the Use of Military Force, and the 2001 Authorization for Use of Military Force : Hearing Before the S. Committee on Armed Services, 113th Cong., May 16, 2013 (Statement by Professor Rosa Brooks, Geo. U. L. Center) [PDF]

, 2013
Mr. Chairman, almost twelve years have gone by since the passage of the AUMF on September 14, 2001. The war in Afghanistan–-the longest war in U.S. history--has begun to wind down.
Brooks, Rosa
core   +1 more source

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source

Dignity in death: International humanitarian law and the protection of the deceased in war

International Review of the Red Cross
When people die in the context of armed conflicts, international humanitarian law (IHL) provides important legal protection for the dead and their families.
Helen Obregón Gieseken, Ximena Londoño
doaj   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Refugees, Internally Displaced Persons, And International Humanitarian Law [PDF]

, 2004
The fact that war is the primary cause of people being uprooted prompts us to ask what protection the law of armed conflict affords refugees and displaced persons. How does humanitarian law protect groups of civilians from being forced to flee?
Bugnion, Francois
core   +1 more source

Cluster‐Mediated Solute Stabilization and Shear‐Bypass Synergistic Strengthening in High‐Alloyed Systems

Advanced Science, EarlyView.
This study demonstrates that in high‐alloy systems, nanoclusters with high solute tolerance can effectively suppress compositional segregation. This mitigation leads to a concurrent 18.7% increase in strength and 41.5% improvement in ductility, which is attributed to a shear‐bypass synergistic strengthening mechanism. The findings provide a new pathway
Wei Yu, Yu Bai, Jiawen Li, Kaixi Jiang, Hai Hao, Tao Jiang, Shunan Zhang, Yong Li, Zhaodong Wang, Kai Zhao, Shiwei Li   +10 more
wiley   +1 more source

Introduction: Targeting in an Asymmetrical World [PDF]

, 2012
This is the introduction to a collection of articles to be published in the Valparaiso University Law Review. The articles address the challenges presented by non-traditional warfare and non-traditional combatants in the contexts of the War on Terror and
Telman, D. A. Jeremy
core   +3 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source